Abstract
S-phenylmercapturic acid (S-PMA) was measured in urine from 145 subjects exposed to low benzene concentrations in the air (C(I), benzene). The 8-h, time-weighted exposure intensity of individual workers was monitored by means of charcoal tubes and subsequent gas-chromatographic analysis after desorption with CS2. S-PMA excretion level in urine was determined by high- performance liquid chromatography with fluorescence detection. The following linear correlation was found between S-PMA concentrations in urine and benzene concentrations in the breathing zone: log(S-PMA, μg/g creatinine)=0.712 log (C(I)-benzene, ppm) + 1.644 (n=145, r=0.74, P
| Original language | English |
|---|---|
| Pages (from-to) | 329-334 |
| Number of pages | 6 |
| Journal | Toxicology Letters |
| Volume | 108 |
| Issue number | 2-3 |
| DOIs | |
| Publication status | Published - Sep 5 1999 |
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Keywords
- Benzene
- S-Phenylmercapturic acid
- Urinalysis
ASJC Scopus subject areas
- Toxicology
Cite this
Determination of S-phenylmercapturic acid in urine as an indicator of exposure to benzene. / Ghittori, Sergio; Imbriani, Marcello; Maestri, Luciano; Capodaglio, Emanuele; Cavalleri, Alessandro.
In: Toxicology Letters, Vol. 108, No. 2-3, 05.09.1999, p. 329-334.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Determination of S-phenylmercapturic acid in urine as an indicator of exposure to benzene
AU - Ghittori, Sergio
AU - Imbriani, Marcello
AU - Maestri, Luciano
AU - Capodaglio, Emanuele
AU - Cavalleri, Alessandro
PY - 1999/9/5
Y1 - 1999/9/5
N2 - S-phenylmercapturic acid (S-PMA) was measured in urine from 145 subjects exposed to low benzene concentrations in the air (C(I), benzene). The 8-h, time-weighted exposure intensity of individual workers was monitored by means of charcoal tubes and subsequent gas-chromatographic analysis after desorption with CS2. S-PMA excretion level in urine was determined by high- performance liquid chromatography with fluorescence detection. The following linear correlation was found between S-PMA concentrations in urine and benzene concentrations in the breathing zone: log(S-PMA, μg/g creatinine)=0.712 log (C(I)-benzene, ppm) + 1.644 (n=145, r=0.74, P
AB - S-phenylmercapturic acid (S-PMA) was measured in urine from 145 subjects exposed to low benzene concentrations in the air (C(I), benzene). The 8-h, time-weighted exposure intensity of individual workers was monitored by means of charcoal tubes and subsequent gas-chromatographic analysis after desorption with CS2. S-PMA excretion level in urine was determined by high- performance liquid chromatography with fluorescence detection. The following linear correlation was found between S-PMA concentrations in urine and benzene concentrations in the breathing zone: log(S-PMA, μg/g creatinine)=0.712 log (C(I)-benzene, ppm) + 1.644 (n=145, r=0.74, P
KW - Benzene
KW - S-Phenylmercapturic acid
KW - Urinalysis
UR - http://www.scopus.com/inward/record.url?scp=0032823560&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032823560&partnerID=8YFLogxK
U2 - 10.1016/S0378-4274(99)00106-X
DO - 10.1016/S0378-4274(99)00106-X
M3 - Article
VL - 108
SP - 329
EP - 334
JO - Toxicology Letters
JF - Toxicology Letters
SN - 0378-4274
IS - 2-3
ER -