Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project

M. Bassetti, L. Scudeller, D.R. Giacobbe, F. Lamoth, E. Righi, V. Zuccaro, C. Grecchi, C. Rebuffi, M. Akova, A. Alastruey-Izquierdo, S. Arikan-Akdagli, E. Azoulay, S.I. Blot, O.A. Cornely, C. Lass-Flörl, P. Koehler, M. Cuenca-Estrella, D.W. de Lange, F.G. De Rosa, J.J. De WaeleG. Dimopoulos, J. Garnacho-Montero, M. Hoenigl, S.S. Kanj, J. Maertens, I. Martin-Loeches, P. Muñoz, B.J. Kullberg, C. Agvald-Ohman, G. Poulakou, J. Rello, M. Sanguinetti, F.S. Taccone, J.-F. Timsit, A. Torres, J.A. Vazquez, T. Calandra, from the Study Group for Infections in Critically Ill Patients (ESGCIP), the Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology, Infectious Diseases (ESCMID), the European Society of Intensive Care Medicine (ESICM), the European Confederation of Medical Mycology (ECMM), the Mycoses Study Group Education, Research Consortium (MSGERC)

Research output: Contribution to journalArticle

Abstract

Background: The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU). Objectives: To develop a standard set of definitions for IFD in critically ill adult patients in ICU. Methods: Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1-9 scale trough a dedicated questionnaire, in two rounds: one remote and one face-to-face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments. Conclusions: The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings. © 2018 Blackwell Verlag GmbH
Original languageEnglish
JournalMycoses
DOIs
Publication statusPublished - 2018

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Mycoses
Critical Illness
Intensive Care Units
Immunocompromised Host
Infection
Research

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Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project. / Bassetti, M.; Scudeller, L.; Giacobbe, D.R.; Lamoth, F.; Righi, E.; Zuccaro, V.; Grecchi, C.; Rebuffi, C.; Akova, M.; Alastruey-Izquierdo, A.; Arikan-Akdagli, S.; Azoulay, E.; Blot, S.I.; Cornely, O.A.; Lass-Flörl, C.; Koehler, P.; Cuenca-Estrella, M.; de Lange, D.W.; De Rosa, F.G.; De Waele, J.J.; Dimopoulos, G.; Garnacho-Montero, J.; Hoenigl, M.; Kanj, S.S.; Maertens, J.; Martin-Loeches, I.; Muñoz, P.; Kullberg, B.J.; Agvald-Ohman, C.; Poulakou, G.; Rello, J.; Sanguinetti, M.; Taccone, F.S.; Timsit, J.-F.; Torres, A.; Vazquez, J.A.; Calandra, T.; (ESGCIP), from the Study Group for Infections in Critically Ill Patients; Microbiology, the Fungal Infection Study Group (EFISG) of the European Society of Clinical; (ESCMID), Infectious Diseases; (ESICM), the European Society of Intensive Care Medicine; (ECMM), the European Confederation of Medical Mycology; Education, the Mycoses Study Group; (MSGERC), Research Consortium.

In: Mycoses, 2018.

Research output: Contribution to journalArticle

Bassetti, M, Scudeller, L, Giacobbe, DR, Lamoth, F, Righi, E, Zuccaro, V, Grecchi, C, Rebuffi, C, Akova, M, Alastruey-Izquierdo, A, Arikan-Akdagli, S, Azoulay, E, Blot, SI, Cornely, OA, Lass-Flörl, C, Koehler, P, Cuenca-Estrella, M, de Lange, DW, De Rosa, FG, De Waele, JJ, Dimopoulos, G, Garnacho-Montero, J, Hoenigl, M, Kanj, SS, Maertens, J, Martin-Loeches, I, Muñoz, P, Kullberg, BJ, Agvald-Ohman, C, Poulakou, G, Rello, J, Sanguinetti, M, Taccone, FS, Timsit, J-F, Torres, A, Vazquez, JA, Calandra, T, (ESGCIP), FTSGFIICIP, Microbiology, TFISGEFISGOTESOC, (ESCMID), ID, (ESICM), TESOICM, (ECMM), TECOMM, Education, TMSG & (MSGERC), RC 2018, 'Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project', Mycoses. https://doi.org/10.1111/myc.12869
Bassetti, M. ; Scudeller, L. ; Giacobbe, D.R. ; Lamoth, F. ; Righi, E. ; Zuccaro, V. ; Grecchi, C. ; Rebuffi, C. ; Akova, M. ; Alastruey-Izquierdo, A. ; Arikan-Akdagli, S. ; Azoulay, E. ; Blot, S.I. ; Cornely, O.A. ; Lass-Flörl, C. ; Koehler, P. ; Cuenca-Estrella, M. ; de Lange, D.W. ; De Rosa, F.G. ; De Waele, J.J. ; Dimopoulos, G. ; Garnacho-Montero, J. ; Hoenigl, M. ; Kanj, S.S. ; Maertens, J. ; Martin-Loeches, I. ; Muñoz, P. ; Kullberg, B.J. ; Agvald-Ohman, C. ; Poulakou, G. ; Rello, J. ; Sanguinetti, M. ; Taccone, F.S. ; Timsit, J.-F. ; Torres, A. ; Vazquez, J.A. ; Calandra, T. ; (ESGCIP), from the Study Group for Infections in Critically Ill Patients ; Microbiology, the Fungal Infection Study Group (EFISG) of the European Society of Clinical ; (ESCMID), Infectious Diseases ; (ESICM), the European Society of Intensive Care Medicine ; (ECMM), the European Confederation of Medical Mycology ; Education, the Mycoses Study Group ; (MSGERC), Research Consortium. / Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project. In: Mycoses. 2018.
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title = "Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project",
abstract = "Background: The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU). Objectives: To develop a standard set of definitions for IFD in critically ill adult patients in ICU. Methods: Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1-9 scale trough a dedicated questionnaire, in two rounds: one remote and one face-to-face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments. Conclusions: The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings. {\circledC} 2018 Blackwell Verlag GmbH",
author = "M. Bassetti and L. Scudeller and D.R. Giacobbe and F. Lamoth and E. Righi and V. Zuccaro and C. Grecchi and C. Rebuffi and M. Akova and A. Alastruey-Izquierdo and S. Arikan-Akdagli and E. Azoulay and S.I. Blot and O.A. Cornely and C. Lass-Fl{\"o}rl and P. Koehler and M. Cuenca-Estrella and {de Lange}, D.W. and {De Rosa}, F.G. and {De Waele}, J.J. and G. Dimopoulos and J. Garnacho-Montero and M. Hoenigl and S.S. Kanj and J. Maertens and I. Martin-Loeches and P. Mu{\~n}oz and B.J. Kullberg and C. Agvald-Ohman and G. Poulakou and J. Rello and M. Sanguinetti and F.S. Taccone and J.-F. Timsit and A. Torres and J.A. Vazquez and T. Calandra and (ESGCIP), {from the Study Group for Infections in Critically Ill Patients} and Microbiology, {the Fungal Infection Study Group (EFISG) of the European Society of Clinical} and (ESCMID), {Infectious Diseases} and (ESICM), {the European Society of Intensive Care Medicine} and (ECMM), {the European Confederation of Medical Mycology} and Education, {the Mycoses Study Group} and (MSGERC), {Research Consortium}",
note = "cited By 1; Article in Press",
year = "2018",
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language = "English",
journal = "Mycoses",
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TY - JOUR

T1 - Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project

AU - Bassetti, M.

AU - Scudeller, L.

AU - Giacobbe, D.R.

AU - Lamoth, F.

AU - Righi, E.

AU - Zuccaro, V.

AU - Grecchi, C.

AU - Rebuffi, C.

AU - Akova, M.

AU - Alastruey-Izquierdo, A.

AU - Arikan-Akdagli, S.

AU - Azoulay, E.

AU - Blot, S.I.

AU - Cornely, O.A.

AU - Lass-Flörl, C.

AU - Koehler, P.

AU - Cuenca-Estrella, M.

AU - de Lange, D.W.

AU - De Rosa, F.G.

AU - De Waele, J.J.

AU - Dimopoulos, G.

AU - Garnacho-Montero, J.

AU - Hoenigl, M.

AU - Kanj, S.S.

AU - Maertens, J.

AU - Martin-Loeches, I.

AU - Muñoz, P.

AU - Kullberg, B.J.

AU - Agvald-Ohman, C.

AU - Poulakou, G.

AU - Rello, J.

AU - Sanguinetti, M.

AU - Taccone, F.S.

AU - Timsit, J.-F.

AU - Torres, A.

AU - Vazquez, J.A.

AU - Calandra, T.

AU - (ESGCIP), from the Study Group for Infections in Critically Ill Patients

AU - Microbiology, the Fungal Infection Study Group (EFISG) of the European Society of Clinical

AU - (ESCMID), Infectious Diseases

AU - (ESICM), the European Society of Intensive Care Medicine

AU - (ECMM), the European Confederation of Medical Mycology

AU - Education, the Mycoses Study Group

AU - (MSGERC), Research Consortium

N1 - cited By 1; Article in Press

PY - 2018

Y1 - 2018

N2 - Background: The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU). Objectives: To develop a standard set of definitions for IFD in critically ill adult patients in ICU. Methods: Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1-9 scale trough a dedicated questionnaire, in two rounds: one remote and one face-to-face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments. Conclusions: The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings. © 2018 Blackwell Verlag GmbH

AB - Background: The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU). Objectives: To develop a standard set of definitions for IFD in critically ill adult patients in ICU. Methods: Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1-9 scale trough a dedicated questionnaire, in two rounds: one remote and one face-to-face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments. Conclusions: The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings. © 2018 Blackwell Verlag GmbH

U2 - 10.1111/myc.12869

DO - 10.1111/myc.12869

M3 - Article

JO - Mycoses

JF - Mycoses

SN - 0933-7407

ER -