Development and cross-validation of prediction equations for estimating resting energy expenditure in severely obese Caucasian children and adolescents

Stefano Lazzer, Fiorenza Agosti, Alessandra De Col, Alessandro Sartorio

Research output: Contribution to journalArticle

Abstract

The objectives of the present study were to develop and cross-validate new equations for predicting resting energy expenditure (REE) in severely obese children and adolescents, and to determine the accuracy of new equations using the Bland-Altman method. The subjects of the study were 574 obese Caucasian children and adolescents (mean BMI z-score 3.3). REE was determined by indirect calorimetry and body composition by bioelectrical impedance analysis. Equations were derived by stepwise multiple regression analysis using a calibration cohort of 287 subjects and the equations were cross-validated in the remaining 287 subjects. Two new specific equations based on anthropometric parameters were generated as follows: (1) REE = (Sex × 892.68) (Age × 115.93) + (Weight × 54.96) + (Stature × 1816.23) + 1484.50 (R2 0.66; SE 1028.97 kJ); (2) REE = (Sex × 909.12) - (Age × 107.48) + (fat-free mass × 68.39) + (fat mass × 55.19) + 3631.23 (R2 0.66; SE 1034.28 kJ): In the cross-validation group, mean predicted REE values were not significantly different from the mean measured REE for all children and adolescents, as well as for boys and for girls (difference

Original languageEnglish
Pages (from-to)973-979
Number of pages7
JournalBritish Journal of Nutrition
Volume96
Issue number5
DOIs
Publication statusPublished - Nov 2006

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Energy Metabolism
Fats
Indirect Calorimetry
Body Composition
Electric Impedance
Calibration
Regression Analysis
Weights and Measures

Keywords

  • Adolescents
  • Body composition
  • Children
  • Energy expenditure
  • Obesity
  • Prediction equation

ASJC Scopus subject areas

  • Medicine (miscellaneous)

Cite this

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title = "Development and cross-validation of prediction equations for estimating resting energy expenditure in severely obese Caucasian children and adolescents",
abstract = "The objectives of the present study were to develop and cross-validate new equations for predicting resting energy expenditure (REE) in severely obese children and adolescents, and to determine the accuracy of new equations using the Bland-Altman method. The subjects of the study were 574 obese Caucasian children and adolescents (mean BMI z-score 3.3). REE was determined by indirect calorimetry and body composition by bioelectrical impedance analysis. Equations were derived by stepwise multiple regression analysis using a calibration cohort of 287 subjects and the equations were cross-validated in the remaining 287 subjects. Two new specific equations based on anthropometric parameters were generated as follows: (1) REE = (Sex × 892.68) (Age × 115.93) + (Weight × 54.96) + (Stature × 1816.23) + 1484.50 (R2 0.66; SE 1028.97 kJ); (2) REE = (Sex × 909.12) - (Age × 107.48) + (fat-free mass × 68.39) + (fat mass × 55.19) + 3631.23 (R2 0.66; SE 1034.28 kJ): In the cross-validation group, mean predicted REE values were not significantly different from the mean measured REE for all children and adolescents, as well as for boys and for girls (difference",
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AU - De Col, Alessandra

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