TY - JOUR
T1 - Development of a transient monoclonal gammopathy after chemotherapy in a patient with biphenotypic acute leukemia
AU - Guariglia, Roberto
AU - Guastafierro, Salvatore
AU - Annunziata, Silvana
AU - Tirelli, Angelo
PY - 2002
Y1 - 2002
N2 - The development of a IgGk monoclonal gammopathy after a phase of bone marrow aplasia following chemotherapy is described in a patient suffering from biphenotypic acute leukemia (BAL). Paraprotein was followed by the relapse of the disease and disappeared during a further chemotherapy. Paraprotein could have been caused by an additional chemotherapy-induced genetic mutation or by a dysfunction in T-B cooperation observed in the phase of reconstitution of the immune system after medullar aplasia.
AB - The development of a IgGk monoclonal gammopathy after a phase of bone marrow aplasia following chemotherapy is described in a patient suffering from biphenotypic acute leukemia (BAL). Paraprotein was followed by the relapse of the disease and disappeared during a further chemotherapy. Paraprotein could have been caused by an additional chemotherapy-induced genetic mutation or by a dysfunction in T-B cooperation observed in the phase of reconstitution of the immune system after medullar aplasia.
KW - Biphenotypic acute leukemia
KW - Chemotherapy
KW - Monoclonal gammopathy
KW - Paraprotein
UR - http://www.scopus.com/inward/record.url?scp=0036196383&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036196383&partnerID=8YFLogxK
U2 - 10.1080/10428190290006314
DO - 10.1080/10428190290006314
M3 - Article
C2 - 11999585
AN - SCOPUS:0036196383
VL - 43
SP - 441
EP - 443
JO - Leukemia and Lymphoma
JF - Leukemia and Lymphoma
SN - 1042-8194
IS - 2
ER -