Development of an Entirely Subcutaneous Implantable Cardioverter-Defibrillator

Pier Paolo Lupo, Gabriele Pelissero, Hussam Ali, Rick Sanghera, Riccardo Cappato

Research output: Contribution to journalArticlepeer-review


The recent advent of an entirely subcutaneous implantable defibrillator (ICD) has provided a relevant contribution to the debate concerning the use of ICD therapy in patients at high risk for death. Although conventional transvenous ICDs have proven very effective during the past 23 years, they still appear to be limited by nontrivial acute and long-term complications. This study delineates some of the historical and current issues characterizing the advent of the subcutaneous ICD system in daily clinical practice. Subcutaneous ICDs have proven effective in more than 1100 patients worldwide and appear to be competitive with transvenous ICD in all clinical conditions not requiring antibradycardia, antitachycardia, or cardiac resynchronization pacing.

Original languageEnglish
Pages (from-to)493-497
Number of pages5
JournalProgress in Cardiovascular Diseases
Issue number6
Publication statusPublished - May 2012


  • Implantable cardioverter-defibrillator
  • Prophylaxis
  • Subcutaneous
  • Sudden death

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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