Development of interactive algorithm for clinical management of acute events related to sickle cell disease in emergency department

Gian Luca Forni, Gabriele Finco, Giovanna Graziadei, Manuela Balocco, Paolo Rigano, Silverio Perrotta, Oliviero Olivieri, Maria Domenica Cappellini, Lucia De Franceschi

Research output: Contribution to journalArticle

Abstract

Sickle cell disease (SCD ORPHA232; OMIM 603903) is a rare hereditary red cell disorder, which global distribution is changed in the last decade due to immigration-fluxes from endemic areas to Western-countries. One of the main clinical manifestations of SCD are the acute painful vaso-occlusive crisis, which cause frequent accesses of SCD patients to the emergency departments (EDs). This has generated the requirement of feasible tools for emergency givers. In the context of the scientific-Italian-Society for the study of Thalassemias and Hemoglobinopathies (SITE), we developed an algorithm with interactive windows to guide physicians in managing SCD patients in EDs.

Original languageEnglish
Article number91
JournalOrphanet Journal of Rare Diseases
Volume9
Issue number1
DOIs
Publication statusPublished - Jun 23 2014

Keywords

  • Acute vaso-occlusive crisis
  • Emergency departments
  • Pain
  • Sickle cell disease

ASJC Scopus subject areas

  • Medicine(all)
  • Genetics(clinical)
  • Pharmacology (medical)

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