Development of paediatric non-stage prognosticator guidelines for population-based cancer registries and updates to the 2014 Toronto Paediatric Cancer Stage Guidelines.

Sumit Gupta, Joanne Aitken, Ute Bartels, Nickhill Bhakta, Mihaela Bucurenci, James D. Brierley, Beatriz De Camargo, Eric Chokunonga, Jessica Clymer, Dana Coza, Chris Fraser, Soad Fuentes-Alabi, Gemma Gatta, Thomas Gross, Zsuzsanna Jakab, Betsy Kohler, Tezer Kutluk, Florencia Moreno, Kayo Nakata, Sari NurD. M. Parkin, Lynne Penberthy, Jason Pole, Jenny N. Poynter, Kathy Pritchard-Jones, Oscar Ramirez, Lorna Renner, Eva Steliarova-Foucher, Michael Sullivan, Rajaraman Swaminathan, Liesbet Van Eycken, Tushar Vora, A. L. Frazier

Research output: Contribution to journalArticlepeer-review

Abstract

Population-based cancer registries (PBCRs) generate measures of cancer incidence and survival that are essential for cancer surveillance, research, and cancer control strategies. In 2014, the Toronto Paediatric Cancer Stage Guidelines were developed to standardise how PBCRs collect data on the stage at diagnosis for childhood cancer cases. These guidelines have been implemented in multiple jurisdictions worldwide to facilitate international comparative studies of incidence and outcome. Robust stratification by risk also requires data on key non-stage prognosticators (NSPs). Key experts and stakeholders used a modified Delphi approach to establish principles guiding paediatric cancer NSP data collection. With the use of these principles, recommendations were made on which NSPs should be collected for the major malignancies in children. The 2014 Toronto Stage Guidelines were also reviewed and updated where necessary. Wide adoption of the resultant Paediatric NSP Guidelines and updated Toronto Stage Guidelines will enhance the harmonisation and use of childhood cancer data provided by PBCRs.
Original languageEnglish
JournalThe Lancet Oncology
Issue number9
Publication statusPublished - Sep 1 2020

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