Development of vasculature targeting strategies for the treatment of chronic inflammatory diseases

Girolamo Ranieri, Roberto Ria, Aldo M. Roccaro, Angelo Vacca, Domenico Ribatti

Research output: Contribution to journalArticle

Abstract

The pathogenesis of a number of chronic inflammatory processes can be attributed to prolonged neovascularization. This article reviews recent studies on the vasculature targeting strategies for the treatment of chronic inflammatory diseases. Targeting of the vasculature of inflamed organs could underlie a new pharmacological approach in the treatment of inflammatory diseases by taking advantage of formulations that deliver drugs to blood vessels specifically located at disease sites and to inflammatory cells.

Original languageEnglish
Pages (from-to)13-22
Number of pages10
JournalCurrent Drug Targets: Inflammation and Allergy
Volume4
Issue number1
DOIs
Publication statusPublished - Feb 2005

Keywords

  • Antiangiogenesis
  • Chronic inflammatory diseases
  • Vascular targeting

ASJC Scopus subject areas

  • Immunology and Allergy
  • Pharmacology
  • Immunology

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