Developmental plasticity connects visual cortex to motoneurons after stroke

Anna Basu, Sara Graziadio, Martin Smith, Gavin J. Clowry, Giovanni Cioni, Janet A. Eyre

Research output: Contribution to journalArticlepeer-review

Abstract

We report motor cortical function in the left occipital cortex of a subject who suffered a left middle cerebral artery stroke early in development. Transcranial magnetic stimulation of the left occipital cortex evoked contraction of right hand muscles. Electroencephalogram recorded over the left occipital cortex showed: 1) coherence with electromyogram from a right hand muscle; 2) a typical sensorimotor Mu rhythm at rest that was suppressed during contraction of right hand muscles. This is the first evidence that cortical plasticity extends beyond reshaping of primary sensory cortical fields to respecification of the cortical origin of subcortically projecting pathways.

Original languageEnglish
Pages (from-to)132-136
Number of pages5
JournalAnnals of Neurology
Volume67
Issue number1
DOIs
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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