Developments in virus-like particle-based vaccines for infectious diseases and cancer

Research output: Contribution to journalArticlepeer-review

Abstract

Virus-like particles hold great promise for the development of effective and affordable vaccines. Indeed, virus-like particles are suitable for presentation and efficient delivery of linear as well as conformational antigens to antigen-presenting cells. This will ultimately result in optimal B-cell activation and cross-presentation with both MHC class I and II molecules to prime CD4 + T-helper as well as CD8 + cytotoxic T cells. This article provides an update on the development and use of virus-like particles as vaccine approaches for infectious diseases and cancer.

Original languageEnglish
Pages (from-to)1569-1583
Number of pages15
JournalExpert Review of Vaccines
Volume10
Issue number11
DOIs
Publication statusPublished - Nov 2011

Keywords

  • antigen presentation
  • cancer
  • infectious diseases
  • vaccine
  • virus-like particles

ASJC Scopus subject areas

  • Immunology
  • Drug Discovery
  • Pharmacology
  • Molecular Medicine

Fingerprint

Dive into the research topics of 'Developments in virus-like particle-based vaccines for infectious diseases and cancer'. Together they form a unique fingerprint.

Cite this