Developments in virus-like particle-based vaccines for infectious diseases and cancer

Research output: Contribution to journalArticlepeer-review


Virus-like particles hold great promise for the development of effective and affordable vaccines. Indeed, virus-like particles are suitable for presentation and efficient delivery of linear as well as conformational antigens to antigen-presenting cells. This will ultimately result in optimal B-cell activation and cross-presentation with both MHC class I and II molecules to prime CD4 + T-helper as well as CD8 + cytotoxic T cells. This article provides an update on the development and use of virus-like particles as vaccine approaches for infectious diseases and cancer.

Original languageEnglish
Pages (from-to)1569-1583
Number of pages15
JournalExpert Review of Vaccines
Issue number11
Publication statusPublished - Nov 2011


  • antigen presentation
  • cancer
  • infectious diseases
  • vaccine
  • virus-like particles

ASJC Scopus subject areas

  • Immunology
  • Drug Discovery
  • Pharmacology
  • Molecular Medicine


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