Devic's neuromyelitis optica

Clinical features and prognostic factors

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

Devic's neuromyelitis optica (NMO) onset is characterized by optic neuritis (ON) and transverse myelitis (TM), either simultaneously or in isolation. Thereafter, the course of the disease can be monophasic (no other attack) or relapsing (sequences of ON and TM, no other neurological system involved). The risk of having a relapsing course is related to gender, older age at onset, less severe motor impairment after the myelitic onset, interval length between first and second attack. The risk of an unfavourable evolution (severe disability or death) during a relapsing course is mainly related to high relapse rate during the first two years of the disease. In summary, relapsing NMO patients tend to have a poor prognosis, requiring more effective immunosuppressive treatments.

Original languageEnglish
JournalNeurological Sciences
Volume25
Issue numberSUPPL. 4
DOIs
Publication statusPublished - Nov 2004

Fingerprint

Transverse Myelitis
Neuromyelitis Optica
Optic Neuritis
Immunosuppressive Agents
Age of Onset
Recurrence
Therapeutics

Keywords

  • Devic's disease
  • Myelitis
  • Neuromyelitis optica
  • Optic neuritis
  • Prognosis

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Devic's neuromyelitis optica : Clinical features and prognostic factors. / Bergamaschi, Roberto; Ghezzi, A.

In: Neurological Sciences, Vol. 25, No. SUPPL. 4, 11.2004.

Research output: Contribution to journalArticle

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