Abstract
Devic's neuromyelitis optica (NMO) onset is characterized by optic neuritis (ON) and transverse myelitis (TM), either simultaneously or in isolation. Thereafter, the course of the disease can be monophasic (no other attack) or relapsing (sequences of ON and TM, no other neurological system involved). The risk of having a relapsing course is related to gender, older age at onset, less severe motor impairment after the myelitic onset, interval length between first and second attack. The risk of an unfavourable evolution (severe disability or death) during a relapsing course is mainly related to high relapse rate during the first two years of the disease. In summary, relapsing NMO patients tend to have a poor prognosis, requiring more effective immunosuppressive treatments.
| Original language | English |
|---|---|
| Journal | Neurological Sciences |
| Volume | 25 |
| Issue number | SUPPL. 4 |
| DOIs | |
| Publication status | Published - Nov 2004 |
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Keywords
- Devic's disease
- Myelitis
- Neuromyelitis optica
- Optic neuritis
- Prognosis
ASJC Scopus subject areas
- Neuroscience(all)
- Clinical Neurology
Cite this
Devic's neuromyelitis optica : Clinical features and prognostic factors. / Bergamaschi, Roberto; Ghezzi, A.
In: Neurological Sciences, Vol. 25, No. SUPPL. 4, 11.2004.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Devic's neuromyelitis optica
T2 - Clinical features and prognostic factors
AU - Bergamaschi, Roberto
AU - Ghezzi, A.
PY - 2004/11
Y1 - 2004/11
N2 - Devic's neuromyelitis optica (NMO) onset is characterized by optic neuritis (ON) and transverse myelitis (TM), either simultaneously or in isolation. Thereafter, the course of the disease can be monophasic (no other attack) or relapsing (sequences of ON and TM, no other neurological system involved). The risk of having a relapsing course is related to gender, older age at onset, less severe motor impairment after the myelitic onset, interval length between first and second attack. The risk of an unfavourable evolution (severe disability or death) during a relapsing course is mainly related to high relapse rate during the first two years of the disease. In summary, relapsing NMO patients tend to have a poor prognosis, requiring more effective immunosuppressive treatments.
AB - Devic's neuromyelitis optica (NMO) onset is characterized by optic neuritis (ON) and transverse myelitis (TM), either simultaneously or in isolation. Thereafter, the course of the disease can be monophasic (no other attack) or relapsing (sequences of ON and TM, no other neurological system involved). The risk of having a relapsing course is related to gender, older age at onset, less severe motor impairment after the myelitic onset, interval length between first and second attack. The risk of an unfavourable evolution (severe disability or death) during a relapsing course is mainly related to high relapse rate during the first two years of the disease. In summary, relapsing NMO patients tend to have a poor prognosis, requiring more effective immunosuppressive treatments.
KW - Devic's disease
KW - Myelitis
KW - Neuromyelitis optica
KW - Optic neuritis
KW - Prognosis
UR - http://www.scopus.com/inward/record.url?scp=10044221145&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=10044221145&partnerID=8YFLogxK
U2 - 10.1007/s10072-004-0342-0
DO - 10.1007/s10072-004-0342-0
M3 - Article
C2 - 15727235
AN - SCOPUS:10044221145
VL - 25
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
IS - SUPPL. 4
ER -