Diabetes mellitus and chronic heart failure

Paolo Fumelli, Fabio Romagnoli, Giorgio Carlino, Cristiana Fumelli, Massimo Boemi

Research output: Contribution to journalArticlepeer-review


Cardiovascular disease has a high prevalence in diabetic patients. Diabetes mellitus is an important risk factor for atherosclerosis and coronary disease mainly through obesity, hyperlipidemia, insulin-resistance, hyperinsulinemia, hyperglycemia and altered homeostasis. The correlation between diabetes and chronic heart failure is not widely documented in the literature. According to the Framingham study, the incidence of cardiovascular morbidity per year is 39.1% in diabetic males and 17.2% in diabetic females; chronic heart failure afflicts 7.6% of diabetic males and 11.4% of diabetic females. Actual knowledge about pathophysiology suggests that cardiac involvement in diabetes is not only related to macrovascular injury but also to other factors, such as alterations of autonomic nervous system, that can contribute to diabetic cardiopathy. The present study evaluated the prevalence of chronic heart failure in an Italian diabetic population in order to discuss the rationale of the therapeutic strategies.

Original languageEnglish
Pages (from-to)277-281
Number of pages5
JournalArchives of Gerontology and Geriatrics
Issue number3
Publication statusPublished - Nov 1996


  • Diabetes mellitus
  • Heart failure
  • Ischemic heart disease

ASJC Scopus subject areas

  • Ageing
  • Medicine(all)


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