Despite many advances in the overall treatment of type 1 diabetes mellitus during the last few years, no maior advance has been made in decreasing the mortality rate of diabetic ketoacidosis. A mayor concern is the development of cerebral edema during treatment. The guiding principles of therapy are rehydration, electrolyte replacement, insulin therapy, and treatment of any underlying illnesses. If the patient is in shock, therapy begins with colloids or normal saline administration to support blood pressure. Fluid and electrolyte deficits should be calculated and replaced during 48 hours. Low dose insulin infusion is employed for treatment of hyperglycemia. Neurologic function should be carefully monitored and mannitol administered immediately if cerebral edema is suspected.
|Translated title of the contribution||Diabetic ketoacidosis|
|Number of pages||9|
|Journal||Acta Medica Romana|
|Publication status||Published - 1999|
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