Diagnosis and management of acute mastoiditis in a cohort of Italian children

Paola Marchisio, Sonia Bianchini, Alberto Villani, Giulia Verri, Filippo Bernardi, Alessandro Porta, Paolo Biban, Silvia Caimmi, Lorenzo Iughetti, Andrzej Krzysztofiak, Silvia Garazzino, Benedetta Romanin, Filippo Salvini, Laura Lancella, Susanna Landini, Carlotta Galeone, Susanna Esposito, Nicola Principi

Research output: Contribution to journalArticlepeer-review


Objective: The Italian Society for Pediatric Infectious Diseases created a registry to determine the management of pediatric acute mastoiditis (AM) in Italy. Methods: A cross-sectional survey of paediatricians was conducted to evaluate hospitalization due to AM in Italian pediatric wards between 1 January 2002, and 31 December 2013. Results: A total of 913 children (561 males, 61.4%) were included in this study. The annual number of AM cases significantly increased during the study period (30 in 2002 and 98 in 2013) but only among older children (≥4 years old; p = 0.02). AM complications occurred in 69 (7.6%) of the children and sequelae were observed in 13 (1.4%) patients. Conclusion: The annual number of pediatric AM cases admitted to Italian pediatric wards increased in the past few years; this increase was strictly age-related. The risk of severe AM complications appeared relatively low, and most AM cases could be treated conservatively.

Original languageEnglish
Pages (from-to)1541-1548
Number of pages8
JournalExpert Review of Anti-Infective Therapy
Issue number12
Publication statusPublished - Dec 1 2014


  • Acute mastoiditis
  • Acute otitis media
  • Antibiotic treatment
  • Ear
  • Pediatric otolaryngology
  • Pneumococcal vaccination

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)
  • Microbiology
  • Virology
  • Medicine(all)


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