Diagnosis and management of patients with white-coat and masked hypertension

Giuseppe Mancia, Michele Bombelli, Gino Seravalle, Guido Grassi

Research output: Contribution to journalArticle

50 Citations (Scopus)

Abstract

White-coat hypertension is characterized by an elevation in clinic blood pressure but normal home or ambulatory blood-pressure values, whereas patients with masked hypertension have normal clinic blood pressure and elevated ambulatory or home blood-pressure load. Both white-coat and masked hypertension are frequent clinical entities that need appropriate recognition and a close diagnostic follow-up. White-coat and masked hypertension seem to be associated with organ damage and increased cardiovascular risk, although not invariably. In addition, patients with masked or white-coat hypertension have an increased risk of abnormalities affecting their glucose and lipid profiles. Therefore, the diagnosis of these conditions should be accurate and include the assessment of cardiovascular as well as of metabolic risk. Once diagnosed, first-line therapeutic interventions should be nonpharmacological and aim at lifestyle changes, but drug treatment can be indicated, particularly when the patient's cardiovascular risk profile is elevated or when target-organ damage is detected.

Original languageEnglish
Pages (from-to)686-693
Number of pages8
JournalNature Reviews Cardiology
Volume8
Issue number12
DOIs
Publication statusPublished - Dec 2011

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Masked Hypertension
White Coat Hypertension
Blood Pressure
Life Style
Lipids
Glucose
Therapeutics
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Diagnosis and management of patients with white-coat and masked hypertension. / Mancia, Giuseppe; Bombelli, Michele; Seravalle, Gino; Grassi, Guido.

In: Nature Reviews Cardiology, Vol. 8, No. 12, 12.2011, p. 686-693.

Research output: Contribution to journalArticle

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