Smears from four hundred and nine patients were studied for the presence and typing of HPV by non isotopic NISH. Cases eligible for the study were: a) 170 consecutive smears with classic cytologic signs of HPV associated with GIN; b) 219 consecutive cases with histologic evidence of HPV infection; c) 20 consecutive cases self-referring to colposcopy showing non cytologic or colposcopic abnormalities. Immediately before colposcopy 3 smears were taken from each patient and a NISH assay was performed using a mixer and typing test for HPV. The results showed a limited association of cytologic or histologic evidence of HPV to ISH positivity, especially when non classic morphologic criteria were considered.
|Number of pages||3|
|Journal||Cervix and the Lower Female Genital Tract|
|Publication status||Published - 1994|
- Human papillomavirus
- In situ hybridization
ASJC Scopus subject areas
- Obstetrics and Gynaecology