Diagnostic des lesions infracliniques du sein par IRM dynamique: Resultats d'une etude prospective et multicentrique

Translated title of the contribution: Diagnosis of nonpalpable breast lesions by dynamic MRI: Results of a prospective and multicentric trial

R. Gilles, M. Meunier, Ph Trouffléau, L. Divano, A. Tardivon, D. Vanel, A. Hacourt, S. Neuenschwander, J. Stinès

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To determine the accuracy of dynamic contrast-enhanced subtraction MRI to diagnose nonpalpable breast lesions in a prospective multicenter study. Material and methods: From June to November 1994, 72 patients had a surgical biopsy for a nonpalpable breast lesion and a preoperative dynamic MR after an informed consent was obtained. MR examinations were performed on 0.5, 1 and 1.5T MR unit. Each center underwent dynamic sequences either in spin or gradient echo in T1 weighted images obtained in less than two minutes before and after injection of Gadolinium-DOTA. The presence/absence of contrast enhancement within two minutes after injection of Gadolinium were considered as positive/negative findings respectively. Results: These 72 women had mammographic (n = 30) or ultrasonographic lesions (n = 2). Mammograms showed mass (n = 23), asymmetrical density (n = 2), architectural distorsion (n = 8), clustered microcalcifications (n = 47) or was normal (n = 2). Dynamic Breast MR imaging showed early contrast enhancement in 44 malignant lesions (sensitivity: 89.8%) and 13 benign lesions (specificity: 60.6%). Five intraductal carcinoma of comedo (n = 1) or non-comedo (n = 4) type did not demonstrate any early contrast enhancement. Conclusion: This prospective mulcentric study confirms the high sensitivity of dynamic breast MRI whatever the type of MR unit or sequences.

Translated title of the contributionDiagnosis of nonpalpable breast lesions by dynamic MRI: Results of a prospective and multicentric trial
Original languageFrench
Pages (from-to)293-297
Number of pages5
JournalJournal de Radiologie
Volume78
Issue number4
Publication statusPublished - 1997

Keywords

  • breast diseases
  • breast neoplasms
  • magnetic resonance imaging
  • mammograms
  • ultrasonography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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