Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients

Marco Merli; Laura Galli; Antonella Castagna; Stefania Salpietro; Nicola Gianotti; Emanuela Messina; Andrea Poli; Giulia Morsica; Sabrina Bagaglio; Massimo Cernuschi; Alba Bigoloni; Caterina Uberti-Foppa; Adriano Lazzarin; Hamid Hasson

Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients

Marco Merli, Laura Galli, Antonella Castagna, Stefania Salpietro, Nicola Gianotti, Emanuela Messina, Andrea Poli, Giulia Morsica, Sabrina Bagaglio, Massimo Cernuschi, Alba Bigoloni, Caterina Uberti-Foppa, Adriano Lazzarin, Hamid Hasson

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article

Abstract

We determined the diagnostic accuracy and optimal cut off of three indirect fibrosis biomarkers (APRI, FIB-4, Forns) compared with liver stiffness (LS) for the detection of liver cirrhosis in HIV/HCV-coinfected patients. An observational retrospective study on HIV/HCV-coinfected patients with concomitant LS measurement and APRI, FIB-4 and Forns was performed. The presence of liver cirrhosis was defined as a LS ≥13 KPa. The diagnostic accuracy and optimal cut-off values compared with LS categorization (

Original language	English
Pages (from-to)	110-113
Number of pages	4
Journal	New Microbiologica
Volume	39
Issue number	2
Publication status	Published - Apr 1 2016

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Keywords

Elastography
Hepatitis C
HIV
Liver cirrhosis
Liver fibrosis

ASJC Scopus subject areas

Microbiology (medical)

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Merli, M., Galli, L., Castagna, A., Salpietro, S., Gianotti, N., Messina, E., Poli, A., Morsica, G., Bagaglio, S., Cernuschi, M., Bigoloni, A., Uberti-Foppa, C., Lazzarin, A., & Hasson, H. (2016). Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients. New Microbiologica, 39(2), 110-113.

Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients. / Merli, Marco; Galli, Laura ; Castagna, Antonella; Salpietro, Stefania; Gianotti, Nicola; Messina, Emanuela; Poli, Andrea; Morsica, Giulia; Bagaglio, Sabrina; Cernuschi, Massimo; Bigoloni, Alba; Uberti-Foppa, Caterina; Lazzarin, Adriano; Hasson, Hamid.

In: New Microbiologica, Vol. 39, No. 2, 01.04.2016, p. 110-113.

Research output: Contribution to journal › Article

Merli, Marco ; Galli, Laura ; Castagna, Antonella ; Salpietro, Stefania ; Gianotti, Nicola ; Messina, Emanuela ; Poli, Andrea ; Morsica, Giulia ; Bagaglio, Sabrina ; Cernuschi, Massimo ; Bigoloni, Alba ; Uberti-Foppa, Caterina ; Lazzarin, Adriano ; Hasson, Hamid. / Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients. In: New Microbiologica. 2016 ; Vol. 39, No. 2. pp. 110-113.

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Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients

Abstract

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Keywords

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