Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients

Marco Merli, Laura Galli, Antonella Castagna, Stefania Salpietro, Nicola Gianotti, Emanuela Messina, Andrea Poli, Giulia Morsica, Sabrina Bagaglio, Massimo Cernuschi, Alba Bigoloni, Caterina Uberti-Foppa, Adriano Lazzarin, Hamid Hasson

Research output: Contribution to journalArticle

Abstract

We determined the diagnostic accuracy and optimal cut off of three indirect fibrosis biomarkers (APRI, FIB-4, Forns) compared with liver stiffness (LS) for the detection of liver cirrhosis in HIV/HCV-coinfected patients. An observational retrospective study on HIV/HCV-coinfected patients with concomitant LS measurement and APRI, FIB-4 and Forns was performed. The presence of liver cirrhosis was defined as a LS ≥13 KPa. The diagnostic accuracy and optimal cut-off values compared with LS categorization (

Original languageEnglish
Pages (from-to)110-113
Number of pages4
JournalNew Microbiologica
Volume39
Issue number2
Publication statusPublished - Apr 1 2016

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Keywords

  • Elastography
  • Hepatitis C
  • HIV
  • Liver cirrhosis
  • Liver fibrosis

ASJC Scopus subject areas

  • Microbiology (medical)

Cite this

Merli, M., Galli, L., Castagna, A., Salpietro, S., Gianotti, N., Messina, E., Poli, A., Morsica, G., Bagaglio, S., Cernuschi, M., Bigoloni, A., Uberti-Foppa, C., Lazzarin, A., & Hasson, H. (2016). Diagnostic accuracy of APRI, FIB-4 and forns for the detection of liver cirrhosis in HIV/HCV-coinfected patients. New Microbiologica, 39(2), 110-113.