Accuratezza diagnostica del translucency rendering nella diagnosi differenziale tra polipi e formazioni pseudopolipoidi all'analisi tridimensionale con colografia TC: studio di fattibilità

Translated title of the contribution: Diagnostic accuracy of translucency rendering to differentiate polyps from pseudopolyps at 3D endoluminal CT colonography: A feasibility study

A. Guerrisi, D. Marin, A. Laghi, M. Di Martino, F. Iafrate, R. Iannaccone, C. Catalano, R. Passariello

Research output: Contribution to journalArticle

Abstract

Purpose: The aim of this study was to assess the accuracy of translucency rendering (TR) in computed tomographic (CT) colonography without cathartic preparation using primary 3D reading. Materials and methods: From 350 patients with 482 endoscopically verified polyps, 50 pathologically proven polyps and 50 pseudopolyps were retrospectively examined. For faecal tagging, all patients ingested 140 ml of orally administered iodinated contrast agent (diatrizoate meglumine and diatrizoate sodium) at meals 48 h prior to CT colonography examination and two h prior to scanning. CT colonography was performed using a 64-section CT scanner. Colonoscopy with segmental unblinding was performed within 2 weeks after CT. Three independent radiologists retrospectively evaluated TRCT clonographic images using a dedicated software package (V3D-Colon System). To enable size-dependent statistical analysis, lesions were stratified into the following size categories: small (≤5 mm), intermediate (6-9 mm), and large (≥10 mm). Results: Overall average TR sensitivity for polyp characterisation was 96.6%, and overall average specificity for pseudopolyp characterisation was 91.3%. Overall average diagnostic accuracy (area under the curve) of TR for characterising colonic lesions was 0.97. Conclusions: TR is an accurate tool that facilitates interpretation of images obtained with a primary 3D analysis, thus enabling easy differentiation of polyps from pseudopolyps.

Original languageItalian
Pages (from-to)758-770
Number of pages13
JournalRadiologia Medica
Volume115
Issue number5
DOIs
Publication statusPublished - Aug 2010

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Computed Tomographic Colonography
Feasibility Studies
Polyps
Diatrizoate Meglumine
Cathartics
Colonoscopy
Contrast Media
Area Under Curve
Meals
Reading
Colon
Software
Sodium

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Accuratezza diagnostica del translucency rendering nella diagnosi differenziale tra polipi e formazioni pseudopolipoidi all'analisi tridimensionale con colografia TC : studio di fattibilità. / Guerrisi, A.; Marin, D.; Laghi, A.; Di Martino, M.; Iafrate, F.; Iannaccone, R.; Catalano, C.; Passariello, R.

In: Radiologia Medica, Vol. 115, No. 5, 08.2010, p. 758-770.

Research output: Contribution to journalArticle

Guerrisi, A. ; Marin, D. ; Laghi, A. ; Di Martino, M. ; Iafrate, F. ; Iannaccone, R. ; Catalano, C. ; Passariello, R. / Accuratezza diagnostica del translucency rendering nella diagnosi differenziale tra polipi e formazioni pseudopolipoidi all'analisi tridimensionale con colografia TC : studio di fattibilità. In: Radiologia Medica. 2010 ; Vol. 115, No. 5. pp. 758-770.
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abstract = "Purpose: The aim of this study was to assess the accuracy of translucency rendering (TR) in computed tomographic (CT) colonography without cathartic preparation using primary 3D reading. Materials and methods: From 350 patients with 482 endoscopically verified polyps, 50 pathologically proven polyps and 50 pseudopolyps were retrospectively examined. For faecal tagging, all patients ingested 140 ml of orally administered iodinated contrast agent (diatrizoate meglumine and diatrizoate sodium) at meals 48 h prior to CT colonography examination and two h prior to scanning. CT colonography was performed using a 64-section CT scanner. Colonoscopy with segmental unblinding was performed within 2 weeks after CT. Three independent radiologists retrospectively evaluated TRCT clonographic images using a dedicated software package (V3D-Colon System). To enable size-dependent statistical analysis, lesions were stratified into the following size categories: small (≤5 mm), intermediate (6-9 mm), and large (≥10 mm). Results: Overall average TR sensitivity for polyp characterisation was 96.6{\%}, and overall average specificity for pseudopolyp characterisation was 91.3{\%}. Overall average diagnostic accuracy (area under the curve) of TR for characterising colonic lesions was 0.97. Conclusions: TR is an accurate tool that facilitates interpretation of images obtained with a primary 3D analysis, thus enabling easy differentiation of polyps from pseudopolyps.",
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