Diagnostics of autoimmune encephalitis associated with antibodies against neuronal surface antigens

Luigi Zuliani, Marco Zoccarato, Matteo Gastaldi, Raffaele Iorio, Amelia Evoli, Tiziana Biagioli, Silvia Casagrande, Elena Bazzigaluppi, Raffaella Fazio, Claudia Giannotta, Eduardo Nobile-Orazio, Francesca Andreetta, Ornella Simoncini, Gianna Costa, Sara Mariotto, Sergio Ferrari, Elisabetta Galloni, Michela Marcon, Diego Franciotta, Bruno Giometto

Research output: Contribution to journalReview articlepeer-review

Abstract

This document presents the guidelines for testing antibodies against neuronal surface antigens that have been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on autoimmune encephalitis associated with antibodies against neuronal surface antigens, indications and limits of testing for such antibodies, instructions for result interpretation, and an agreed laboratory protocol (Appendix A) are reported for the communicative community of neurologists and clinical pathologists.

Original languageEnglish
Pages (from-to)225-229
Number of pages5
JournalNeurological Sciences
Volume38
DOIs
Publication statusPublished - Oct 1 2017

Keywords

  • Anti-contactin-associated protein-like 2 (CASPR2) antibodies
  • Anti-leucine-rich glioma inactivated 1 (LGI1) antibodies
  • Anti-N-methyl-d-aspartate receptor (NMDA-R) antibodies
  • Cell-based assays
  • Laboratory diagnostics

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

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