Diagnostics of the neuromyelitis optica spectrum disorders (NMOSD)

Diego Franciotta, Matteo Gastaldi, Arianna Sala, Francesca Andreetta, Elena Rinaldi, Maddalena Ruggieri, Rosaria Leante, Gianna Costa, Tiziana Biagioli, Luca Massacesi, Elena Bazzigaluppi, Raffaella Fazio, Sara Mariotto, Sergio Ferrari, Elisabetta Galloni, Francesco Perini, Elisabetta Zardini, Luigi Zuliani, Marco Zoccarato, Bruno GiomettoAntonio Bertolotto

Research output: Contribution to journalReview article

Abstract

This document presents the guidelines for anti-aquaporin-4 (AQP4) antibody testing that has been developed following a consensus process built on questionnaire-based surveys, internet contacts, and discussions at workshops of the sponsoring Italian Association of Neuroimmunology (AINI) congresses. Essential clinical information on neuromyelitis optica spectrum disorders, indications and limits of anti-AQP4 antibody testing, instructions for result interpretation, and an agreed laboratory protocol (Appendix) are reported for the communicative community of neurologists and clinical pathologists.

Original languageEnglish
Pages (from-to)231-236
Number of pages6
JournalNeurological Sciences
Volume38
DOIs
Publication statusPublished - Oct 1 2017

Keywords

  • Anti-aquaporin-4 antibodies
  • Anti-myelin oligodendrocyte glycoprotein antibodies
  • Cell-based assay
  • Laboratory diagnostics
  • Neurological autoimmune diseases

ASJC Scopus subject areas

  • Dermatology
  • Clinical Neurology
  • Psychiatry and Mental health

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  • Cite this

    Franciotta, D., Gastaldi, M., Sala, A., Andreetta, F., Rinaldi, E., Ruggieri, M., Leante, R., Costa, G., Biagioli, T., Massacesi, L., Bazzigaluppi, E., Fazio, R., Mariotto, S., Ferrari, S., Galloni, E., Perini, F., Zardini, E., Zuliani, L., Zoccarato, M., ... Bertolotto, A. (2017). Diagnostics of the neuromyelitis optica spectrum disorders (NMOSD). Neurological Sciences, 38, 231-236. https://doi.org/10.1007/s10072-017-3027-1