Dialysis modalities for the management of pediatric acute kidney injury: Pediatric Nephrology

L. de Galasso, S. Picca, I. Guzzo

Research output: Contribution to journalArticlepeer-review


Acute kidney injury (AKI) is an increasingly frequent complication among hospitalized children. It is associated with high morbidity and mortality, especially in neonates and children requiring dialysis. The different renal replacement therapy (RRT) options for AKI have expanded from peritoneal dialysis (PD) and intermittent hemodialysis (HD) to continuous RRT (CRRT) and hybrid modalities. Recent advances in the provision of RRT in children allow a higher standard of care for increasingly ill and young patients. In the absence of evidence indicating better survival with any dialysis method, the most appropriate dialysis choice for children with AKI is based on the patient’s characteristics, on dialytic modality performance, and on the institutional resources and local practice. In this review, the available dialysis modalities for pediatric AKI will be discussed, focusing on indications, advantages, and limitations of each of them. © 2019, IPNA.
Original languageEnglish
Pages (from-to)753-765
Number of pages13
JournalPediatr. Nephrol.
Issue number5
Publication statusPublished - 2020


  • AKI
  • Children
  • CRRT
  • Hemodialysis
  • Peritoneal dialysis
  • Regional citrate anticoagulation
  • citric acid
  • dialysis fluid
  • heparin
  • peritoneal dialysis fluid
  • phoxilium
  • acute kidney failure
  • acute kidney tubule necrosis
  • anticoagulation
  • Article
  • catheter infection
  • catheter leakage
  • catheter occlusion
  • catheter thrombosis
  • clearance
  • continuous renal replacement therapy
  • electrolyte disturbance
  • glomerulopathy
  • health care quality
  • hemodialysis
  • hernia
  • human
  • hypotension
  • hypothermia
  • infection
  • multiple organ failure
  • pediatric patient
  • peritoneal dialysis
  • priority journal
  • renal replacement therapy
  • survival
  • treatment indication
  • ultrafiltration
  • vascular access


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