Diastolic dysfunction and baroreflex sensitivity in hypertension

Maria Vittoria Pitzalis, Andrea Passantino, Francesco Massari, Cinzia Forleo, Cataldo Balducci, Giuseppe Santoro, Filippo Mastropasqua, Gianfranco Antonelli, Paolo Rizzon

Research output: Contribution to journalArticlepeer-review


The determinants of diastolic dysfunction in patients with systemic hypertension are not completely known. To evaluate the possible role of age, arterial blood pressure, and baroreflex heart rate response impairment in causing diastolic dysfunction, we studied 61 patients (42 male; mean±SD age, 43.9±12 years) with newly recognized and therefore previously untreated systemic hypertension. Diastolic dysfunction was evaluated by means of Doppler echocardiography (and diagnosed as such when the early to atrial peak velocity ratio corrected to heart rate was

Original languageEnglish
Pages (from-to)1141-1145
Number of pages5
Issue number5
Publication statusPublished - May 1999


  • Baroreflex
  • Blood pressure monitoring, ambulatory
  • Hypertension, systemic
  • Ventricular function, left

ASJC Scopus subject areas

  • Internal Medicine


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