Abstract
We studied left ventricular diastolic function by equilibrium gated radionuclide angiography in patients as follows: 75 with acute myocardial infarction (AMI), 35 with anterior or anteroseptal necrosis (Group A) and 40 with inferior, inferolateral, or posterior necrosis (Group I). The ejection fraction (EF) was lower in Group A than Group I (41.9 ± 2.5 vs. 57.1 ± 2.0%, p <0.001), as was peak diastolic filling rate normalized to end diastolic volume (PDFR-EDV/sec) (1.9 ± 0.1 vs. 2.4 ± 0.1 EDV/sec, p <0.05). PDFR normalized to stroke volume was similar in both groups. An excellent linear correlation was found between EF and PDFR-EDV/sec in the total study population. Isovolumic relaxation period (IRP) was beyond our upper normal value of 94 msec in 64% of patients and it was shorter in Group A than I (95.8 ± 12.7 vs. 147.0 ± 13.6 msec, p <0.05). The presence of shorter IRP in Group A than in I is probably a result of an earlier mitral valve opening as a consequence of higher left atrial pressure.
| Original language | English |
|---|---|
| Pages (from-to) | 1786-1789 |
| Number of pages | 4 |
| Journal | Journal of Nuclear Medicine |
| Volume | 29 |
| Issue number | 11 |
| Publication status | Published - 1988 |
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ASJC Scopus subject areas
- Radiological and Ultrasound Technology
Cite this
Diastolic function in acute myocardial infarction : A radionuclide study. / Bonaduce, D.; Morgano, G.; Petretta, M.; Arrichiello, P.; Conforti, G.; Betocchi, S.; Salvatore, M.; Chiariello, M.
In: Journal of Nuclear Medicine, Vol. 29, No. 11, 1988, p. 1786-1789.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Diastolic function in acute myocardial infarction
T2 - A radionuclide study
AU - Bonaduce, D.
AU - Morgano, G.
AU - Petretta, M.
AU - Arrichiello, P.
AU - Conforti, G.
AU - Betocchi, S.
AU - Salvatore, M.
AU - Chiariello, M.
PY - 1988
Y1 - 1988
N2 - We studied left ventricular diastolic function by equilibrium gated radionuclide angiography in patients as follows: 75 with acute myocardial infarction (AMI), 35 with anterior or anteroseptal necrosis (Group A) and 40 with inferior, inferolateral, or posterior necrosis (Group I). The ejection fraction (EF) was lower in Group A than Group I (41.9 ± 2.5 vs. 57.1 ± 2.0%, p <0.001), as was peak diastolic filling rate normalized to end diastolic volume (PDFR-EDV/sec) (1.9 ± 0.1 vs. 2.4 ± 0.1 EDV/sec, p <0.05). PDFR normalized to stroke volume was similar in both groups. An excellent linear correlation was found between EF and PDFR-EDV/sec in the total study population. Isovolumic relaxation period (IRP) was beyond our upper normal value of 94 msec in 64% of patients and it was shorter in Group A than I (95.8 ± 12.7 vs. 147.0 ± 13.6 msec, p <0.05). The presence of shorter IRP in Group A than in I is probably a result of an earlier mitral valve opening as a consequence of higher left atrial pressure.
AB - We studied left ventricular diastolic function by equilibrium gated radionuclide angiography in patients as follows: 75 with acute myocardial infarction (AMI), 35 with anterior or anteroseptal necrosis (Group A) and 40 with inferior, inferolateral, or posterior necrosis (Group I). The ejection fraction (EF) was lower in Group A than Group I (41.9 ± 2.5 vs. 57.1 ± 2.0%, p <0.001), as was peak diastolic filling rate normalized to end diastolic volume (PDFR-EDV/sec) (1.9 ± 0.1 vs. 2.4 ± 0.1 EDV/sec, p <0.05). PDFR normalized to stroke volume was similar in both groups. An excellent linear correlation was found between EF and PDFR-EDV/sec in the total study population. Isovolumic relaxation period (IRP) was beyond our upper normal value of 94 msec in 64% of patients and it was shorter in Group A than I (95.8 ± 12.7 vs. 147.0 ± 13.6 msec, p <0.05). The presence of shorter IRP in Group A than in I is probably a result of an earlier mitral valve opening as a consequence of higher left atrial pressure.
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M3 - Article
VL - 29
SP - 1786
EP - 1789
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
SN - 0161-5505
IS - 11
ER -