Dienogest treatment improves quality of life in women with endometriosis

Stefano Luisi; Fabio Parazzini; Stefano Angioni; Saverio Arena; Paolo Berretta; Massimo Candiani; Vito Cela; Luigi Fedele; Pietro Litta; Antonio Maiorana; Luigi Nappi; Maria Grazia Porpora; Maurizio Rosati; Fulvio Zullo; Claudia Tosti; Felice Petraglia

doi:10.5301/je.5000232

Dienogest treatment improves quality of life in women with endometriosis

Stefano Luisi, Fabio Parazzini, Stefano Angioni, Saverio Arena, Paolo Berretta, Massimo Candiani, Vito Cela, Luigi Fedele, Pietro Litta, Antonio Maiorana, Luigi Nappi, Maria Grazia Porpora, Maurizio Rosati, Fulvio Zullo, Claudia Tosti, Felice Petraglia

Research output: Contribution to journal › Article › peer-review

Abstract

Background: The aim of this study was to assess the efficacy of dienogest treatment in improving quality of life in women with endometriosis. Methods: This was a prospective observational multicenter study at the universities of Siena, Milano, Cagliari, Perugia, Busto Arstizio, Pisa, Padova, Palermo, Foggia, Roma, Pescara and Catanzaro, including 142 patients with a diagnosis of endometriosis who received dienogest 2 mg once daily, for up to 90 days. Each patient underwent an evaluation of pelvic pain measured by visual analogue scale (VAS) from 0 to 10 points, and of quality of life measured by a mental and physical index before and after treatment. Results: The mean ± SD of VAS was 8.2 ± 1.6 in women with endometriosis, and this progressively and signifi- cantly decreased to 5.9 ± 2.6 at the end of the study. Mental index score values increased from 39.0 ± 9.8 to 46.0 ± 9.1 (p

Original language	English
Pages (from-to)	124-128
Number of pages	5
Journal	Journal of Endometriosis and Pelvic Pain Disorders
Volume	7
Issue number	4
DOIs	https://doi.org/10.5301/je.5000232
Publication status	Published - 2015

Keywords

Dienogest
Endometriosis
Pelvic pain
Quality of life
Stress

ASJC Scopus subject areas

Obstetrics and Gynaecology

Access to Document

10.5301/je.5000232

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Luisi, S., Parazzini, F., Angioni, S., Arena, S., Berretta, P., Candiani, M., Cela, V., Fedele, L., Litta, P., Maiorana, A., Nappi, L., Porpora, M. G., Rosati, M., Zullo, F., Tosti, C., & Petraglia, F. (2015). Dienogest treatment improves quality of life in women with endometriosis. Journal of Endometriosis and Pelvic Pain Disorders, 7(4), 124-128. https://doi.org/10.5301/je.5000232

Dienogest treatment improves quality of life in women with endometriosis. / Luisi, Stefano; Parazzini, Fabio; Angioni, Stefano; Arena, Saverio; Berretta, Paolo; Candiani, Massimo; Cela, Vito; Fedele, Luigi; Litta, Pietro; Maiorana, Antonio; Nappi, Luigi; Porpora, Maria Grazia; Rosati, Maurizio; Zullo, Fulvio; Tosti, Claudia; Petraglia, Felice.

In: Journal of Endometriosis and Pelvic Pain Disorders, Vol. 7, No. 4, 2015, p. 124-128.

Research output: Contribution to journal › Article › peer-review

Luisi, S, Parazzini, F, Angioni, S, Arena, S, Berretta, P, Candiani, M, Cela, V, Fedele, L, Litta, P, Maiorana, A, Nappi, L, Porpora, MG, Rosati, M, Zullo, F, Tosti, C & Petraglia, F 2015, 'Dienogest treatment improves quality of life in women with endometriosis', Journal of Endometriosis and Pelvic Pain Disorders, vol. 7, no. 4, pp. 124-128. https://doi.org/10.5301/je.5000232

Luisi, Stefano ; Parazzini, Fabio ; Angioni, Stefano ; Arena, Saverio ; Berretta, Paolo ; Candiani, Massimo ; Cela, Vito ; Fedele, Luigi ; Litta, Pietro ; Maiorana, Antonio ; Nappi, Luigi ; Porpora, Maria Grazia ; Rosati, Maurizio ; Zullo, Fulvio ; Tosti, Claudia ; Petraglia, Felice. / Dienogest treatment improves quality of life in women with endometriosis. In: Journal of Endometriosis and Pelvic Pain Disorders. 2015 ; Vol. 7, No. 4. pp. 124-128.

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