Diet, obesity and breast cancer: An update

Alessandro Cappellani, Maria Di Vita, Antonio Zanghi, Andrea Cavallaro, Gaetano Piccolo, Massimiliano Veroux, Massimiliano Berretta, Michele Malaguarnera, Vincenzo Canzonieri, Emanuele Lo Menzo

Research output: Contribution to journalArticlepeer-review


Numerous studies indagated the relationship between dietary pattern or specific nutrients and breast cancer (BC) risk and survival. Different ethnic o social groups show differences in breast cancer incidence that could be explained by different dietary patterns. Furthermore, many nutrients could reasonably increase the risk of cancer because of their content of carcinogens or their precursors as well as of promoting substances. However, the only convincing evidences linking life style to increased BC risk are related to obesity and moderate intake of alcohol and limited to postmenopause. Saturated fat, red meat, high temperature cooking have been indicated as possible risk factors, but adjusted analyses have not confirmed this association or have limited the relationship to specific subgroups. Even the protective effect of fiber, fruit, vegetables and phytoestrogens has been suggested but not definitively demonstrated. Thus, healthy dietary patterns, with abstention from alcohol and weight control, reduce the risk of cancer or at least improve the survival of affected women by reducing the incidence of comorbidities.

Original languageEnglish
Pages (from-to)90-108
Number of pages19
JournalFrontiers in Bioscience - Scholar
Volume4 S
Issue number1
Publication statusPublished - Jan 1 2012


  • Body weight
  • Breast neoplasms
  • Control
  • Diet
  • Epidemiology
  • Etiology
  • Food habits
  • Prevention
  • Review

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)
  • Medicine(all)


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