Abitudini alimentari e malattie cardiovascolari: L'esperienza della collaborazione epic-Italia

Translated title of the contribution: Dietary Habits and cardiovascular disease: The experience of epic Italian collaboration

Amalia Mattiello, Paolo Chiodini, Maria Santucci De Magistris, Vittorio Krogh, Sara Grioni, Francesco Fasanelli, Paolo Vineis, Calogero Saieva, Benedetto Bendinelli, Graziella Fresco, Maria Concetta Giurdanella, Salvatore Panico

Research output: Contribution to journalArticlepeer-review


OBJECTIVES: To report and evaluate the evidence produced by the EPIC Italian collaboration (EPICOR Project) on the dietary determinants of cardiovascular diseases in Italy. DESIGN: prospective study carried out in a large Italian population, composed by cohorts recruited in Northern, Central and Southern Italy. SETTING AND PARTICIPANTS: data on dietary habits collected at the baseline observation through standardised questionnaires on 47,749 free-living adults at the time of the recruitment of the study (1993-1998). MAIN OUTCOME MEASURES: major coronary and cerebrovascular events (acute coronary syndrome, PTCA, CABG, ischemic and haemor- rhagic stroke, TEA of supraortic vessels) identified at follow-up. The longitudinal analyses here reported have measured risks through the use of multivariate Cox regression models, adjusted for potential confounders. RESULTS: The longitudinal analyses of EPICOR indicate that Mediter- ranean-oriented dietary habits, measured through specific indicators and the consumption of various typical food, are able to reduce coronary and cerebrovascular risks, and that this protection is possible even nowadays, although many changes in diet have occurred in the last decades in Italy. Habitual consumption of plant origin products, including all foods with low glycemic index, is an advantage for cardiovascular risk. CONCLUSIONS: The EPICOR Project is the largest, long-lasting Italian study on the relationship between diet and cardiovascular diseases. It is also the study with the greater number of observed variables. Its results point out the importance to support preventive programmes and industrial policies able to favour a dietary style inspired to the Italian Mediterranean tradition.

Translated title of the contributionDietary Habits and cardiovascular disease: The experience of epic Italian collaboration
Original languageItalian
Pages (from-to)339-344
Number of pages6
JournalEpidemiologia e prevenzione
Issue number5-6
Publication statusPublished - Sep 1 2015

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health


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