Dietary intake of calcium, vitamin D, phosphorus and the risk of prostate cancer

Alessandra Tavani, Paola Bertuccio, Cristina Bosetti, Renato Talamini, Eva Negri, Silvia Franceschi, Maurizio Montella, Carlo La Vecchia

Research output: Contribution to journalArticlepeer-review


Objectives: A relation of prostate cancer risk with calcium, vitamin D and phosphorus has been suggested, but remains controversial. Methods: A case-control study was conducted in Italy in 1991-2002. Cases were 1294 men with incident prostate cancer, and controls were 1451 men admitted to hospital for acute non-neoplastic diseases. Odds ratios (OR) and the corresponding 95% confidence intervals (CI) were estimated using unconditional multiple logistic regression. Results: Compared to the lowest one quintile of dietary calcium intake the OR was 1.18 for the highest, 1.01 for an increment of 622 mg/day of calcium, and 1.29 (95% CI 0.78-2.13) for 2000 mg/day or more of calcium. The OR of prostate cancer for the highest quintile of dietary intake of vitamin D and phosphorus were 1.33 and 1.20 respectively. Conclusions: This study shows no material association of dietary intake of calcium, vitamin D and phosphorus with prostate cancer risk.

Original languageEnglish
Pages (from-to)27-33
Number of pages7
JournalEuropean Urology
Issue number1
Publication statusPublished - Jul 2005


  • Calcium
  • Case-control study
  • Phosphorus
  • Prostate cancer
  • Risk factors
  • Vitamin D

ASJC Scopus subject areas

  • Urology


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