Abstract
Background: We studied the relationship between dietary intake of vegetables and fruit and lung cancer risk in Harbin, Heilongjiang province, northeast China, an area with a very high baseline risk of lung cancer in both sexes. Patients and methods: We used data from a case-control study, conducted from 1987 to 1990, among 218 cases with incident, histologically confirmed lung cancer and 436 controls admitted to the same hospitals as cases with non-neoplastic, non-lung diseases unrelated to smoking and other potential risk factors for lung cancer. Results: Compared with the lowest tertile of intake of vegetables, fruit or both, the multivariate odds ratios (ORs) for the highest tertile of intake were 0.39 [95% confidence interval (CI) 0.25-0.62], 0.73 (95% CI 0.48-1.11) and 0.40 (95% CI 0.25-0.63), respectively. In particular, high intake of Chinese cabbage (OR = 0.53), chives (OR = 0.54), carrots (OR = 0.51) and celery (OR = 0.40) was inversely associated with lung cancer. The OR was more than six-fold elevated for smokers reporting low intake of vegetables, and more than four-fold elevated for smokers reporting low intake of fruit, as compared with never smokers reporting high intake of these items. Conclusion: In agreement with previous studies, we found an inverse relation between vegetable and fruit intake and lung cancer risk in both strata of current and never smokers.
| Original language | English |
|---|---|
| Pages (from-to) | 388-392 |
| Number of pages | 5 |
| Journal | Annals of Oncology |
| Volume | 18 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Feb 2007 |
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Keywords
- Allium vegetables
- China
- Diet
- Fruit intake
- Lung cancer
- Vegetable intake
ASJC Scopus subject areas
- Oncology
- Cancer Research
Cite this
Dietary intake of fruit and vegetable and lung cancer risk : A case-control study in Harbin, northeast China. / Galeone, C.; Negri, E.; Pelucchi, C.; La Vecchia, C.; Bosetti, C.; Hu, J.
In: Annals of Oncology, Vol. 18, No. 2, 02.2007, p. 388-392.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dietary intake of fruit and vegetable and lung cancer risk
T2 - A case-control study in Harbin, northeast China
AU - Galeone, C.
AU - Negri, E.
AU - Pelucchi, C.
AU - La Vecchia, C.
AU - Bosetti, C.
AU - Hu, J.
PY - 2007/2
Y1 - 2007/2
N2 - Background: We studied the relationship between dietary intake of vegetables and fruit and lung cancer risk in Harbin, Heilongjiang province, northeast China, an area with a very high baseline risk of lung cancer in both sexes. Patients and methods: We used data from a case-control study, conducted from 1987 to 1990, among 218 cases with incident, histologically confirmed lung cancer and 436 controls admitted to the same hospitals as cases with non-neoplastic, non-lung diseases unrelated to smoking and other potential risk factors for lung cancer. Results: Compared with the lowest tertile of intake of vegetables, fruit or both, the multivariate odds ratios (ORs) for the highest tertile of intake were 0.39 [95% confidence interval (CI) 0.25-0.62], 0.73 (95% CI 0.48-1.11) and 0.40 (95% CI 0.25-0.63), respectively. In particular, high intake of Chinese cabbage (OR = 0.53), chives (OR = 0.54), carrots (OR = 0.51) and celery (OR = 0.40) was inversely associated with lung cancer. The OR was more than six-fold elevated for smokers reporting low intake of vegetables, and more than four-fold elevated for smokers reporting low intake of fruit, as compared with never smokers reporting high intake of these items. Conclusion: In agreement with previous studies, we found an inverse relation between vegetable and fruit intake and lung cancer risk in both strata of current and never smokers.
AB - Background: We studied the relationship between dietary intake of vegetables and fruit and lung cancer risk in Harbin, Heilongjiang province, northeast China, an area with a very high baseline risk of lung cancer in both sexes. Patients and methods: We used data from a case-control study, conducted from 1987 to 1990, among 218 cases with incident, histologically confirmed lung cancer and 436 controls admitted to the same hospitals as cases with non-neoplastic, non-lung diseases unrelated to smoking and other potential risk factors for lung cancer. Results: Compared with the lowest tertile of intake of vegetables, fruit or both, the multivariate odds ratios (ORs) for the highest tertile of intake were 0.39 [95% confidence interval (CI) 0.25-0.62], 0.73 (95% CI 0.48-1.11) and 0.40 (95% CI 0.25-0.63), respectively. In particular, high intake of Chinese cabbage (OR = 0.53), chives (OR = 0.54), carrots (OR = 0.51) and celery (OR = 0.40) was inversely associated with lung cancer. The OR was more than six-fold elevated for smokers reporting low intake of vegetables, and more than four-fold elevated for smokers reporting low intake of fruit, as compared with never smokers reporting high intake of these items. Conclusion: In agreement with previous studies, we found an inverse relation between vegetable and fruit intake and lung cancer risk in both strata of current and never smokers.
KW - Allium vegetables
KW - China
KW - Diet
KW - Fruit intake
KW - Lung cancer
KW - Vegetable intake
UR - http://www.scopus.com/inward/record.url?scp=33847278291&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33847278291&partnerID=8YFLogxK
U2 - 10.1093/annonc/mdl387
DO - 10.1093/annonc/mdl387
M3 - Article
C2 - 17060488
AN - SCOPUS:33847278291
VL - 18
SP - 388
EP - 392
JO - Annals of Oncology
JF - Annals of Oncology
SN - 0923-7534
IS - 2
ER -