Dietary intake of fruit and vegetable and lung cancer risk: A case-control study in Harbin, northeast China

C. Galeone, E. Negri, C. Pelucchi, C. La Vecchia, C. Bosetti, J. Hu

Research output: Contribution to journalArticle

Abstract

Background: We studied the relationship between dietary intake of vegetables and fruit and lung cancer risk in Harbin, Heilongjiang province, northeast China, an area with a very high baseline risk of lung cancer in both sexes. Patients and methods: We used data from a case-control study, conducted from 1987 to 1990, among 218 cases with incident, histologically confirmed lung cancer and 436 controls admitted to the same hospitals as cases with non-neoplastic, non-lung diseases unrelated to smoking and other potential risk factors for lung cancer. Results: Compared with the lowest tertile of intake of vegetables, fruit or both, the multivariate odds ratios (ORs) for the highest tertile of intake were 0.39 [95% confidence interval (CI) 0.25-0.62], 0.73 (95% CI 0.48-1.11) and 0.40 (95% CI 0.25-0.63), respectively. In particular, high intake of Chinese cabbage (OR = 0.53), chives (OR = 0.54), carrots (OR = 0.51) and celery (OR = 0.40) was inversely associated with lung cancer. The OR was more than six-fold elevated for smokers reporting low intake of vegetables, and more than four-fold elevated for smokers reporting low intake of fruit, as compared with never smokers reporting high intake of these items. Conclusion: In agreement with previous studies, we found an inverse relation between vegetable and fruit intake and lung cancer risk in both strata of current and never smokers.

Original languageEnglish
Pages (from-to)388-392
Number of pages5
JournalAnnals of Oncology
Volume18
Issue number2
DOIs
Publication statusPublished - Feb 2007

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Vegetables
Case-Control Studies
Fruit
China
Lung Neoplasms
Odds Ratio
Confidence Intervals
Chive
Apium graveolens
Daucus carota
Brassica
Smoking

Keywords

  • Allium vegetables
  • China
  • Diet
  • Fruit intake
  • Lung cancer
  • Vegetable intake

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Dietary intake of fruit and vegetable and lung cancer risk : A case-control study in Harbin, northeast China. / Galeone, C.; Negri, E.; Pelucchi, C.; La Vecchia, C.; Bosetti, C.; Hu, J.

In: Annals of Oncology, Vol. 18, No. 2, 02.2007, p. 388-392.

Research output: Contribution to journalArticle

Galeone, C. ; Negri, E. ; Pelucchi, C. ; La Vecchia, C. ; Bosetti, C. ; Hu, J. / Dietary intake of fruit and vegetable and lung cancer risk : A case-control study in Harbin, northeast China. In: Annals of Oncology. 2007 ; Vol. 18, No. 2. pp. 388-392.
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