Abstract
Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95%CI: 0.82–1.59) and water from foods (OR = 0.88; 95%CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95%CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.
| Original language | English |
|---|---|
| Pages (from-to) | 151-156 |
| Number of pages | 6 |
| Journal | Cancer Epidemiology |
| Volume | 45 |
| DOIs | |
| Publication status | Published - Dec 1 2016 |
Fingerprint
Keywords
- Bladder cancer
- Case–control study
- Diet
- Dietary water intake
- Fluids
ASJC Scopus subject areas
- Epidemiology
- Oncology
- Cancer Research
Cite this
Dietary water intake and bladder cancer risk : An Italian case–control study. / Di Maso, Matteo; Bosetti, Cristina; Taborelli, Martina; Montella, Maurizio; Libra, Massimo; Zucchetto, Antonella; Turati, Federica; Parpinel, Maria; Negri, Eva Vanna Lorenza; Tavani, Alessandra; Serraino, Diego; Ferraroni, M.; La Vecchia, Carlo; Polesel, Jerry.
In: Cancer Epidemiology, Vol. 45, 01.12.2016, p. 151-156.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Dietary water intake and bladder cancer risk
T2 - An Italian case–control study
AU - Di Maso, Matteo
AU - Bosetti, Cristina
AU - Taborelli, Martina
AU - Montella, Maurizio
AU - Libra, Massimo
AU - Zucchetto, Antonella
AU - Turati, Federica
AU - Parpinel, Maria
AU - Negri, Eva Vanna Lorenza
AU - Tavani, Alessandra
AU - Serraino, Diego
AU - Ferraroni, M.
AU - La Vecchia, Carlo
AU - Polesel, Jerry
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95%CI: 0.82–1.59) and water from foods (OR = 0.88; 95%CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95%CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.
AB - Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95%CI: 0.82–1.59) and water from foods (OR = 0.88; 95%CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95%CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.
KW - Bladder cancer
KW - Case–control study
KW - Diet
KW - Dietary water intake
KW - Fluids
UR - http://www.scopus.com/inward/record.url?scp=84994662311&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84994662311&partnerID=8YFLogxK
U2 - 10.1016/j.canep.2016.09.015
DO - 10.1016/j.canep.2016.09.015
M3 - Article
VL - 45
SP - 151
EP - 156
JO - Cancer Epidemiology
JF - Cancer Epidemiology
SN - 1877-7821
ER -