Dietary water intake and bladder cancer risk: An Italian case–control study

Matteo Di Maso, Cristina Bosetti, Martina Taborelli, Maurizio Montella, Massimo Libra, Antonella Zucchetto, Federica Turati, Maria Parpinel, Eva Vanna Lorenza Negri, Alessandra Tavani, Diego Serraino, M. Ferraroni, Carlo La Vecchia, Jerry Polesel

Research output: Contribution to journalArticle

Abstract

Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95%CI: 0.82–1.59) and water from foods (OR = 0.88; 95%CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95%CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalCancer Epidemiology
Volume45
DOIs
Publication statusPublished - Dec 1 2016

Fingerprint

Urinary Bladder Neoplasms
Food and Beverages
Drinking
Odds Ratio
Water
Confidence Intervals
Beverages
Logistic Models
Food
Vegetables
Italy
Databases
Control Groups

Keywords

  • Bladder cancer
  • Case–control study
  • Diet
  • Dietary water intake
  • Fluids

ASJC Scopus subject areas

  • Epidemiology
  • Oncology
  • Cancer Research

Cite this

Dietary water intake and bladder cancer risk : An Italian case–control study. / Di Maso, Matteo; Bosetti, Cristina; Taborelli, Martina; Montella, Maurizio; Libra, Massimo; Zucchetto, Antonella; Turati, Federica; Parpinel, Maria; Negri, Eva Vanna Lorenza; Tavani, Alessandra; Serraino, Diego; Ferraroni, M.; La Vecchia, Carlo; Polesel, Jerry.

In: Cancer Epidemiology, Vol. 45, 01.12.2016, p. 151-156.

Research output: Contribution to journalArticle

Di Maso, M, Bosetti, C, Taborelli, M, Montella, M, Libra, M, Zucchetto, A, Turati, F, Parpinel, M, Negri, EVL, Tavani, A, Serraino, D, Ferraroni, M, La Vecchia, C & Polesel, J 2016, 'Dietary water intake and bladder cancer risk: An Italian case–control study', Cancer Epidemiology, vol. 45, pp. 151-156. https://doi.org/10.1016/j.canep.2016.09.015
Di Maso, Matteo ; Bosetti, Cristina ; Taborelli, Martina ; Montella, Maurizio ; Libra, Massimo ; Zucchetto, Antonella ; Turati, Federica ; Parpinel, Maria ; Negri, Eva Vanna Lorenza ; Tavani, Alessandra ; Serraino, Diego ; Ferraroni, M. ; La Vecchia, Carlo ; Polesel, Jerry. / Dietary water intake and bladder cancer risk : An Italian case–control study. In: Cancer Epidemiology. 2016 ; Vol. 45. pp. 151-156.
@article{5d9b3154ca6d4e9e8365e657eb1b4183,
title = "Dietary water intake and bladder cancer risk: An Italian case–control study",
abstract = "Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95{\%} confidence intervals (95{\%}CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7{\%} of water intake derived from beverages and 35.4{\%} from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95{\%}CI: 0.82–1.59) and water from foods (OR = 0.88; 95{\%}CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95{\%}CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.",
keywords = "Bladder cancer, Case–control study, Diet, Dietary water intake, Fluids",
author = "{Di Maso}, Matteo and Cristina Bosetti and Martina Taborelli and Maurizio Montella and Massimo Libra and Antonella Zucchetto and Federica Turati and Maria Parpinel and Negri, {Eva Vanna Lorenza} and Alessandra Tavani and Diego Serraino and M. Ferraroni and {La Vecchia}, Carlo and Jerry Polesel",
year = "2016",
month = "12",
day = "1",
doi = "10.1016/j.canep.2016.09.015",
language = "English",
volume = "45",
pages = "151--156",
journal = "Cancer Epidemiology",
issn = "1877-7821",
publisher = "Elsevier Ltd",

}

TY - JOUR

T1 - Dietary water intake and bladder cancer risk

T2 - An Italian case–control study

AU - Di Maso, Matteo

AU - Bosetti, Cristina

AU - Taborelli, Martina

AU - Montella, Maurizio

AU - Libra, Massimo

AU - Zucchetto, Antonella

AU - Turati, Federica

AU - Parpinel, Maria

AU - Negri, Eva Vanna Lorenza

AU - Tavani, Alessandra

AU - Serraino, Diego

AU - Ferraroni, M.

AU - La Vecchia, Carlo

AU - Polesel, Jerry

PY - 2016/12/1

Y1 - 2016/12/1

N2 - Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95%CI: 0.82–1.59) and water from foods (OR = 0.88; 95%CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95%CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.

AB - Previous studies on the relationship between fluid intake and risk of bladder cancer have generally focused on beverages, and results have been inconsistent. We investigated the relationship between water intake and bladder cancer risk, considering water from both beverages and foods. Between 2003 and 2014 we conducted a multicenter hospital-based case–control study in Italy on 690 cases and 665 frequency-matched controls. Water intake for beverages and foods was computed using the Italian food composition database. Odds ratios (ORs) and the corresponding 95% confidence intervals (95%CIs) for water intake were estimated by unconditional multiple logistic regression models, adjusting for major risk factors for bladder cancer. In the control group, the 64.7% of water intake derived from beverages and 35.4% from foods. Comparing the highest with the lowest quartile of intake, water from beverages (OR = 1.14; 95%CI: 0.82–1.59) and water from foods (OR = 0.88; 95%CI: 0.61–1.28) were not significantly associated with bladder cancer risk. Some specific water sources showed significant associations with bladder cancer risk (e.g. water from vegetables, OR = 0.58; 95%CI: 0.40–0.86). However, these associations may be due to the effect of other components contained in beverages and foods rather than to the water content itself. Considering the intakes of water from both beverages and foods, total water intake was not associated with bladder cancer risk.

KW - Bladder cancer

KW - Case–control study

KW - Diet

KW - Dietary water intake

KW - Fluids

UR - http://www.scopus.com/inward/record.url?scp=84994662311&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84994662311&partnerID=8YFLogxK

U2 - 10.1016/j.canep.2016.09.015

DO - 10.1016/j.canep.2016.09.015

M3 - Article

VL - 45

SP - 151

EP - 156

JO - Cancer Epidemiology

JF - Cancer Epidemiology

SN - 1877-7821

ER -