Differences in heart rate variability during haemodialysis and haemofiltration

Simonetta Genovesi, Oscar Bracchi, Paolo Fabbrini, Elena Luisetto, Maria Rosa Viganó, Daniela Lucini, Mara Malacarne, Andrea Stella, Massimo Pagani

Research output: Contribution to journalArticlepeer-review


Background. The aim of our study was to evaluate whether convective (haemofiltration, Hf) and diffusive (haemodialysis, Hd) dialysis techniques induce different patterns of long- and short-term autonomic adjustments in haemodynamically stable dialysis patients. Methods: Ten haemodynamically stable Hd patients were studied. Each patient underwent a block of six Hd sessions, then was switched to six Hf. During the last session of each dialytic treatment, continuous beat to beat measurements of systolic arterial pressure (SAP) and heart rate (HR) were performed. Spectral analysis of heart rate variability (HRV) was made before and during the treatment to evaluate the modification of autonomic nervous system activity. Results: Baseline values of plasma sodium, body weight, HR and SAP were not different for the two considered methods of dialysis, while the baseline values of normalized LF were significantly higher in Hf as compared to Hd and the opposite was observed for HF powers (P

Original languageEnglish
Pages (from-to)2256-2262
Number of pages7
JournalNephrology Dialysis Transplantation
Issue number8
Publication statusPublished - Aug 2007


  • Haemodialysis
  • Haemofiltration
  • Heart rate variability
  • Hemodynamic stability
  • Spectral analysis

ASJC Scopus subject areas

  • Nephrology
  • Transplantation


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