Differences in latency to first pharmacological treatment (duration of untreated illness) in anxiety disorders: A study on patients with panic disorder, generalized anxiety disorder and obsessive-compulsive disorder

Bernardo Dell'Osso, Giulia Camuri, Beatrice Benatti, Massimiliano Buoli, A. Carlo Altamura

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: The latency to first pharmacological treatment (duration of untreated illness or 'DUI') is supposed to play a major role in terms of outcome in psychotic conditions. Interest in the field of affective disorders and, in particular, of duration of untreated anxiety, has been recently registered as well. However, a preliminary epidemiologic investigation of the phenomenon is necessary. The present study was aimed to investigate and compare age at onset, age at first pharmacological treatment and DUI in a sample of patients affected by different anxiety disorders. DUI was defined as the interval between the onset of the specific anxiety disorder and the administration of the first adequate pharmacological treatment in compliant subjects. Methods: Study sample included 350 patients, of both sexes, with a DSM-IV-TR diagnosis of panic disorder (n=138), generalized anxiety disorder (n=127) and obsessive-compulsive disorder (n=85). Results: Panic disorder was associated with the shortest DUI (39.5 months), whereas obsessive-compulsive disorder was associated with the longest latency to treatment (94.5 months) (F=13.333; P

Original languageEnglish
Pages (from-to)374-380
Number of pages7
JournalEarly Intervention in Psychiatry
Volume7
Issue number4
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Duration of untreated illness
  • Early intervention
  • Generalized anxiety disorder
  • Obsessive-compulsive disorder
  • Panic disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Phychiatric Mental Health
  • Biological Psychiatry

Fingerprint Dive into the research topics of 'Differences in latency to first pharmacological treatment (duration of untreated illness) in anxiety disorders: A study on patients with panic disorder, generalized anxiety disorder and obsessive-compulsive disorder'. Together they form a unique fingerprint.

Cite this