Differences in post-prandial increase of serum bile acids after oral ursodeoxycholic acid in healthy subjects, cirrhotic patients and ileal-resected patients

R. Testa, F. Dellepiane, C. Mansi

Research output: Contribution to journalArticlepeer-review

Abstract

In healthy subjects and in patients with cirrhosis the difference between post-prandial serum bile acid after oral ursodeoxycholic acid and post-prandial before UDCA is statistically significant. In patients with ileal resection the difference is not significant. Our results show that the post-prandial SBA after UDCA in healthy subjects and those with cirrhosis show a statistically significant increase compared with ileal-resected patients. Moreover there is no difference between healthy subjects and cirrhotics. This seems to show that the increase after UDCA does not depend on hepatic function, but rather on intestinal absorption. Nevertheless, the post-prandial SBA before UDCA in our ileal-resected patients proved higher than in healthy subjects.

Original languageEnglish
Pages (from-to)639
Number of pages1
JournalIRCS Medical Science
Volume8
Issue number9
Publication statusPublished - 1980

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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