Differences in resource use and costs of dementia care between European countries

Baseline data from the ICTUS study

Anders Gustavsson, L. Jonsson, T. Rapp, E. Reynish, P. J. Ousset, S. Andrieu, C. Cantet, B. Winblad, B. Vellas, A. Wimo, B. Vellas, R. W. Jones, A. Burns, R. Bullock, A. Malick, E. Salmon, G. Waldemar, J. F. Dartigues, F. Pasquier, J. Touchon & 24 others Ph Robert, A. S. Rigaud, V. Camus, G. Stiens, L. Frölich, M. Tsolaki, G. Frisoni, G. Rodriguez, A. Cherubini, L. Spiru, B. Boada, A. Salva, E. Agüera-Morales, J. M. Ribera-Casado, P. M. Lage, B. Winblad, D. Zekry, P. Scheltens, M. Olde-Rikkert, C. Cortes, C. Cantet, P. J. Ousset, C. Caillaud, E. Reynish

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

Objectives: This study aimed to estimate the costs of formal and informal care of patients with Alzheimer's disease, to compare care costs across European countries and identify potential differences in cost patterns between countries and regions. Setting: The ICTUS study is a prospective, naturalistic observational study conducted in specialised memory clinics in 12 European countries. In total, 1385 patients diagnosed with Alzheimer's disease were enrolled at baseline. All subjects had a reliable informant (primary caregiver) and informed consent was obtained from patients or their primary caregiver. Main outcome measures: Resource utilization data was captured with the RUD Lite (Resource Utilization in Dementia) instrument and caregiver burden with the Zarit Burden Interview (ZBI). Patient disease severity was measured with the Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-cog), Katz' index (PADL), Instrumental activities of daily living (IADL) scale and Neuropsychiatric inventory (NPI). Results: The mean annual cost of care per patient was estimated to €7,820 (95% CI: €7,194-€8,446), whereof 54% were costs of informal care, 16% direct medical costs and 30% community care costs. There were substantial differences in total resource utilization and also in the balance between formal and informal care between Northern, Western and Southern Europe. PADL scores were strongly associated with formal care costs while IADL scores correlated strongly with informal care costs. Conclusions: Costs of Alzheimer's Disease are high across European countries. Activities of daily living is an important determinant of care costs. Formal care service use is lower and informal care higher in Southern Europe compared to Western and Northern Europe. Differences in resource utilization patterns are important to consider in international studies of dementia care costs as well as in economic evaluations of new treatments for dementia.

Original languageEnglish
Pages (from-to)648-654
Number of pages7
JournalJournal of Nutrition, Health and Aging
Volume14
Issue number8
DOIs
Publication statusPublished - Aug 2010

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Dementia
Costs and Cost Analysis
Patient Care
Alzheimer Disease
Activities of Daily Living
Caregivers
Cost of Illness
Informed Consent
Cost-Benefit Analysis
Observational Studies
Outcome Assessment (Health Care)
Interviews
Equipment and Supplies

Keywords

  • Alzheimer
  • cost of illness
  • economics

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics
  • Geriatrics and Gerontology

Cite this

Differences in resource use and costs of dementia care between European countries : Baseline data from the ICTUS study. / Gustavsson, Anders; Jonsson, L.; Rapp, T.; Reynish, E.; Ousset, P. J.; Andrieu, S.; Cantet, C.; Winblad, B.; Vellas, B.; Wimo, A.; Vellas, B.; Jones, R. W.; Burns, A.; Bullock, R.; Malick, A.; Salmon, E.; Waldemar, G.; Dartigues, J. F.; Pasquier, F.; Touchon, J.; Robert, Ph; Rigaud, A. S.; Camus, V.; Stiens, G.; Frölich, L.; Tsolaki, M.; Frisoni, G.; Rodriguez, G.; Cherubini, A.; Spiru, L.; Boada, B.; Salva, A.; Agüera-Morales, E.; Ribera-Casado, J. M.; Lage, P. M.; Winblad, B.; Zekry, D.; Scheltens, P.; Olde-Rikkert, M.; Cortes, C.; Cantet, C.; Ousset, P. J.; Caillaud, C.; Reynish, E.

In: Journal of Nutrition, Health and Aging, Vol. 14, No. 8, 08.2010, p. 648-654.

Research output: Contribution to journalArticle

Gustavsson, A, Jonsson, L, Rapp, T, Reynish, E, Ousset, PJ, Andrieu, S, Cantet, C, Winblad, B, Vellas, B, Wimo, A, Vellas, B, Jones, RW, Burns, A, Bullock, R, Malick, A, Salmon, E, Waldemar, G, Dartigues, JF, Pasquier, F, Touchon, J, Robert, P, Rigaud, AS, Camus, V, Stiens, G, Frölich, L, Tsolaki, M, Frisoni, G, Rodriguez, G, Cherubini, A, Spiru, L, Boada, B, Salva, A, Agüera-Morales, E, Ribera-Casado, JM, Lage, PM, Winblad, B, Zekry, D, Scheltens, P, Olde-Rikkert, M, Cortes, C, Cantet, C, Ousset, PJ, Caillaud, C & Reynish, E 2010, 'Differences in resource use and costs of dementia care between European countries: Baseline data from the ICTUS study', Journal of Nutrition, Health and Aging, vol. 14, no. 8, pp. 648-654. https://doi.org/10.1007/s12603-010-0311-7
Gustavsson, Anders ; Jonsson, L. ; Rapp, T. ; Reynish, E. ; Ousset, P. J. ; Andrieu, S. ; Cantet, C. ; Winblad, B. ; Vellas, B. ; Wimo, A. ; Vellas, B. ; Jones, R. W. ; Burns, A. ; Bullock, R. ; Malick, A. ; Salmon, E. ; Waldemar, G. ; Dartigues, J. F. ; Pasquier, F. ; Touchon, J. ; Robert, Ph ; Rigaud, A. S. ; Camus, V. ; Stiens, G. ; Frölich, L. ; Tsolaki, M. ; Frisoni, G. ; Rodriguez, G. ; Cherubini, A. ; Spiru, L. ; Boada, B. ; Salva, A. ; Agüera-Morales, E. ; Ribera-Casado, J. M. ; Lage, P. M. ; Winblad, B. ; Zekry, D. ; Scheltens, P. ; Olde-Rikkert, M. ; Cortes, C. ; Cantet, C. ; Ousset, P. J. ; Caillaud, C. ; Reynish, E. / Differences in resource use and costs of dementia care between European countries : Baseline data from the ICTUS study. In: Journal of Nutrition, Health and Aging. 2010 ; Vol. 14, No. 8. pp. 648-654.
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abstract = "Objectives: This study aimed to estimate the costs of formal and informal care of patients with Alzheimer's disease, to compare care costs across European countries and identify potential differences in cost patterns between countries and regions. Setting: The ICTUS study is a prospective, naturalistic observational study conducted in specialised memory clinics in 12 European countries. In total, 1385 patients diagnosed with Alzheimer's disease were enrolled at baseline. All subjects had a reliable informant (primary caregiver) and informed consent was obtained from patients or their primary caregiver. Main outcome measures: Resource utilization data was captured with the RUD Lite (Resource Utilization in Dementia) instrument and caregiver burden with the Zarit Burden Interview (ZBI). Patient disease severity was measured with the Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-cog), Katz' index (PADL), Instrumental activities of daily living (IADL) scale and Neuropsychiatric inventory (NPI). Results: The mean annual cost of care per patient was estimated to €7,820 (95{\%} CI: €7,194-€8,446), whereof 54{\%} were costs of informal care, 16{\%} direct medical costs and 30{\%} community care costs. There were substantial differences in total resource utilization and also in the balance between formal and informal care between Northern, Western and Southern Europe. PADL scores were strongly associated with formal care costs while IADL scores correlated strongly with informal care costs. Conclusions: Costs of Alzheimer's Disease are high across European countries. Activities of daily living is an important determinant of care costs. Formal care service use is lower and informal care higher in Southern Europe compared to Western and Northern Europe. Differences in resource utilization patterns are important to consider in international studies of dementia care costs as well as in economic evaluations of new treatments for dementia.",
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author = "Anders Gustavsson and L. Jonsson and T. Rapp and E. Reynish and Ousset, {P. J.} and S. Andrieu and C. Cantet and B. Winblad and B. Vellas and A. Wimo and B. Vellas and Jones, {R. W.} and A. Burns and R. Bullock and A. Malick and E. Salmon and G. Waldemar and Dartigues, {J. F.} and F. Pasquier and J. Touchon and Ph Robert and Rigaud, {A. S.} and V. Camus and G. Stiens and L. Fr{\"o}lich and M. Tsolaki and G. Frisoni and G. Rodriguez and A. Cherubini and L. Spiru and B. Boada and A. Salva and E. Ag{\"u}era-Morales and Ribera-Casado, {J. M.} and Lage, {P. M.} and B. Winblad and D. Zekry and P. Scheltens and M. Olde-Rikkert and C. Cortes and C. Cantet and Ousset, {P. J.} and C. Caillaud and E. Reynish",
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T1 - Differences in resource use and costs of dementia care between European countries

T2 - Baseline data from the ICTUS study

AU - Gustavsson, Anders

AU - Jonsson, L.

AU - Rapp, T.

AU - Reynish, E.

AU - Ousset, P. J.

AU - Andrieu, S.

AU - Cantet, C.

AU - Winblad, B.

AU - Vellas, B.

AU - Wimo, A.

AU - Vellas, B.

AU - Jones, R. W.

AU - Burns, A.

AU - Bullock, R.

AU - Malick, A.

AU - Salmon, E.

AU - Waldemar, G.

AU - Dartigues, J. F.

AU - Pasquier, F.

AU - Touchon, J.

AU - Robert, Ph

AU - Rigaud, A. S.

AU - Camus, V.

AU - Stiens, G.

AU - Frölich, L.

AU - Tsolaki, M.

AU - Frisoni, G.

AU - Rodriguez, G.

AU - Cherubini, A.

AU - Spiru, L.

AU - Boada, B.

AU - Salva, A.

AU - Agüera-Morales, E.

AU - Ribera-Casado, J. M.

AU - Lage, P. M.

AU - Winblad, B.

AU - Zekry, D.

AU - Scheltens, P.

AU - Olde-Rikkert, M.

AU - Cortes, C.

AU - Cantet, C.

AU - Ousset, P. J.

AU - Caillaud, C.

AU - Reynish, E.

PY - 2010/8

Y1 - 2010/8

N2 - Objectives: This study aimed to estimate the costs of formal and informal care of patients with Alzheimer's disease, to compare care costs across European countries and identify potential differences in cost patterns between countries and regions. Setting: The ICTUS study is a prospective, naturalistic observational study conducted in specialised memory clinics in 12 European countries. In total, 1385 patients diagnosed with Alzheimer's disease were enrolled at baseline. All subjects had a reliable informant (primary caregiver) and informed consent was obtained from patients or their primary caregiver. Main outcome measures: Resource utilization data was captured with the RUD Lite (Resource Utilization in Dementia) instrument and caregiver burden with the Zarit Burden Interview (ZBI). Patient disease severity was measured with the Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-cog), Katz' index (PADL), Instrumental activities of daily living (IADL) scale and Neuropsychiatric inventory (NPI). Results: The mean annual cost of care per patient was estimated to €7,820 (95% CI: €7,194-€8,446), whereof 54% were costs of informal care, 16% direct medical costs and 30% community care costs. There were substantial differences in total resource utilization and also in the balance between formal and informal care between Northern, Western and Southern Europe. PADL scores were strongly associated with formal care costs while IADL scores correlated strongly with informal care costs. Conclusions: Costs of Alzheimer's Disease are high across European countries. Activities of daily living is an important determinant of care costs. Formal care service use is lower and informal care higher in Southern Europe compared to Western and Northern Europe. Differences in resource utilization patterns are important to consider in international studies of dementia care costs as well as in economic evaluations of new treatments for dementia.

AB - Objectives: This study aimed to estimate the costs of formal and informal care of patients with Alzheimer's disease, to compare care costs across European countries and identify potential differences in cost patterns between countries and regions. Setting: The ICTUS study is a prospective, naturalistic observational study conducted in specialised memory clinics in 12 European countries. In total, 1385 patients diagnosed with Alzheimer's disease were enrolled at baseline. All subjects had a reliable informant (primary caregiver) and informed consent was obtained from patients or their primary caregiver. Main outcome measures: Resource utilization data was captured with the RUD Lite (Resource Utilization in Dementia) instrument and caregiver burden with the Zarit Burden Interview (ZBI). Patient disease severity was measured with the Mini-Mental State Examination (MMSE), Alzheimer's Disease Assessment Scale-Cognitive subscale (ADAS-cog), Katz' index (PADL), Instrumental activities of daily living (IADL) scale and Neuropsychiatric inventory (NPI). Results: The mean annual cost of care per patient was estimated to €7,820 (95% CI: €7,194-€8,446), whereof 54% were costs of informal care, 16% direct medical costs and 30% community care costs. There were substantial differences in total resource utilization and also in the balance between formal and informal care between Northern, Western and Southern Europe. PADL scores were strongly associated with formal care costs while IADL scores correlated strongly with informal care costs. Conclusions: Costs of Alzheimer's Disease are high across European countries. Activities of daily living is an important determinant of care costs. Formal care service use is lower and informal care higher in Southern Europe compared to Western and Northern Europe. Differences in resource utilization patterns are important to consider in international studies of dementia care costs as well as in economic evaluations of new treatments for dementia.

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KW - cost of illness

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