Les différences hommes-femmes dans la perception et la modulation de la douleur

Translated title of the contribution: Differences in the way men and women perceive and deal with pain

A. M. Aloisi, I. Ceccarelli, P. Fiorenzani, C. Bonezzi

Research output: Contribution to journalArticlepeer-review


The presence of sex differences in pain are well known. In this review some former and recent data on several aspects of pain research relative to sex differences are highlighted. In particular the limbic system, including the hypothalamus and the hippocampus, with its involvement in arousal and attention, is confirmed to show several sex differences revealed with behavioral and hormonal parameters. The main gonadal hormones estradiol and testosterone are described in their pro-algesic or ipo-algesic effects in both sexes. On the whole these data support the clinical evidence of a higher "ability" of females to retain painful stimuli able to explain the higher incidence of chronic pain in this sex.

Translated title of the contributionDifferences in the way men and women perceive and deal with pain
Original languageFrench
Pages (from-to)140-145
Number of pages6
JournalDouleur et Analgesie
Issue number3
Publication statusPublished - Sep 2009


  • CNS
  • Gonadal hormones
  • Sex differences

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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