Different approaches of symbolic dynamics to quantify heart rate complexity

Dirk Cysarz, Alberto Porta, Nicola Montano, Peter Van Leeuwen, Jürgen Kurths, Niels Wessel

Research output: Contribution to journalArticle

Abstract

The analysis of symbolic dynamics applied to physiological time series is able to retrieve information about dynamical properties of the underlying system that cannot be gained with standard methods like e.g. spectral analysis. Different approaches for the transformation of the original time series to the symbolic time series have been proposed. Yet the differences between the approaches are unknown. In this study three different transformation methods are investigated: (1) symbolization according to the deviation from the average time series, (2) symbolization according to several equidistant levels between the minimum and maximum of the time series, (3) binary symbolization of the first derivative of the time series. Each method was applied to the cardiac interbeat interval series RR(i) and its difference ΔRR(I) of 17 healthy subjects obtained during head-up tilt testing. The symbolic dynamics of each method is analyzed by means of the occurrence of short sequences ('words') of length 3. The occurrence of words is grouped according to words without variations of the symbols (0V%), words with one variation (1V%), two like variations (2LV%) and two unlike variations (2UV%). Linear regression analysis showed that for method 1 0V%, 1V%, 2LV% and 2UV% changed with increasing tilt angle. For method 2 0V%, 2LV% and 2UV% changed with increasing tilt angle and method 3 showed changes for 0V% and 1V%. In conclusion, all methods are capable of reflecting changes of the cardiac autonomic nervous system during head-up tilt. All methods show that even the analysis of very short symbolic sequences is capable of tracking changes of the cardiac autonomic regulation during head-up tilt testing.

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Time series
Heart Rate
Head
Neurology
Testing
Linear regression
Regression analysis
Spectrum analysis
Autonomic Nervous System
Derivatives
Linear Models
Healthy Volunteers
Regression Analysis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

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title = "Different approaches of symbolic dynamics to quantify heart rate complexity",
abstract = "The analysis of symbolic dynamics applied to physiological time series is able to retrieve information about dynamical properties of the underlying system that cannot be gained with standard methods like e.g. spectral analysis. Different approaches for the transformation of the original time series to the symbolic time series have been proposed. Yet the differences between the approaches are unknown. In this study three different transformation methods are investigated: (1) symbolization according to the deviation from the average time series, (2) symbolization according to several equidistant levels between the minimum and maximum of the time series, (3) binary symbolization of the first derivative of the time series. Each method was applied to the cardiac interbeat interval series RR(i) and its difference ΔRR(I) of 17 healthy subjects obtained during head-up tilt testing. The symbolic dynamics of each method is analyzed by means of the occurrence of short sequences ('words') of length 3. The occurrence of words is grouped according to words without variations of the symbols (0V{\%}), words with one variation (1V{\%}), two like variations (2LV{\%}) and two unlike variations (2UV{\%}). Linear regression analysis showed that for method 1 0V{\%}, 1V{\%}, 2LV{\%} and 2UV{\%} changed with increasing tilt angle. For method 2 0V{\%}, 2LV{\%} and 2UV{\%} changed with increasing tilt angle and method 3 showed changes for 0V{\%} and 1V{\%}. In conclusion, all methods are capable of reflecting changes of the cardiac autonomic nervous system during head-up tilt. All methods show that even the analysis of very short symbolic sequences is capable of tracking changes of the cardiac autonomic regulation during head-up tilt testing.",
author = "Dirk Cysarz and Alberto Porta and Nicola Montano and {Van Leeuwen}, Peter and J{\"u}rgen Kurths and Niels Wessel",
year = "2013",
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language = "English",
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AU - Wessel, Niels

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