TY - JOUR
T1 - Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients
T2 - A six-month, randomized clinical trial
AU - Cicero, Arrigo F G
AU - Derosa, Giuseppe
AU - Manca, Marco
AU - Bove, Marilisa
AU - Borghi, Claudio
AU - Gaddi, Antonio V.
PY - 2007/8
Y1 - 2007/8
N2 - In the setting of a six-month, open-label clinical trial, 141 consecutively enrolled, hypertensive, overweight patients were randomized to the oral ingestion of psyllium powder or guar gum 3.5 gr t.i.d., to be taken 20 min before the main two meals, or to standard diet. Both fibers improved significantly BMI, FPG, FPI, HOMA Index, HbA1c, LDL-C, and ApoB. Psyllium supplementation only exerted a significant improvement in plasma TG concentration, in SBP and DBP. In our study, six-month supplementation with psyllium fiber, but not with guar fiber nor standard diet, appears to significantly reduce both SBP and DBP in hypertensive overweight subjects.
AB - In the setting of a six-month, open-label clinical trial, 141 consecutively enrolled, hypertensive, overweight patients were randomized to the oral ingestion of psyllium powder or guar gum 3.5 gr t.i.d., to be taken 20 min before the main two meals, or to standard diet. Both fibers improved significantly BMI, FPG, FPI, HOMA Index, HbA1c, LDL-C, and ApoB. Psyllium supplementation only exerted a significant improvement in plasma TG concentration, in SBP and DBP. In our study, six-month supplementation with psyllium fiber, but not with guar fiber nor standard diet, appears to significantly reduce both SBP and DBP in hypertensive overweight subjects.
KW - Hypercholesterolemia
KW - Hyperglycemia
KW - Hypertension
KW - Overweight
KW - Soluble fibers
UR - http://www.scopus.com/inward/record.url?scp=34548321367&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34548321367&partnerID=8YFLogxK
U2 - 10.1080/10641960701578378
DO - 10.1080/10641960701578378
M3 - Article
C2 - 17729055
AN - SCOPUS:34548321367
VL - 29
SP - 383
EP - 394
JO - Clinical and Experimental Hypertension
JF - Clinical and Experimental Hypertension
SN - 1064-1963
IS - 6
ER -