Different modes of intermittent positive pressure ventilation (IPPV) in acute exacerbations of COLD patients

K. Foglio, E. Clini, M. Vitacca

Research output: Contribution to journalArticle

Abstract

Patients with chronic obstructive lung disease may suffer from acute exacerbations of their disease, which may lead to acute respiratory failure necessitating endotracheal intubation and mechanical ventilation. We have compared retrospectively the results obtained with nasal positive pressure ventilation and those of standard medical therapy in acute relapses of severe COLD. The study showed that nasal IPPV (NIPPV) in control mode delivered for approximately 1 h, four times daily, six days a week over a 21 day period, does not result in independent improvement of acute exacerbation of COLD. In the next study the data seem to indicate, in apparent contrast, a marked reduction in the need for endotracheal intubation using noninvasive ventilation, both with assist-control and pressure support noninvasive modes, in comparison with an historical control group. We did not find a significant difference in the success rate of the two modes, but compliance to noninvasive ventilation was better with pressure support. In the former study patients showing neurological signs end requiring mechanical ventilation were excluded, while in the last study patients were selected on the basis of necessity of mechanical ventilation. The fact that in the last study, ventilation was applied by face mask instead of nasal mask may have influenced results. Further efforts are required to determine whether non-invasive ventilation is more a preventive measure to avoid endotracheal intubation, or is another means of delivering ventilatory support.

Original languageEnglish
Pages (from-to)556-557
Number of pages2
JournalMonaldi Archives for Chest Disease - Cardiac Series
Volume49
Issue number6
Publication statusPublished - 1994

Fingerprint

Intermittent Positive-Pressure Ventilation
Noninvasive Ventilation
Intratracheal Intubation
Nose
Artificial Respiration
Masks
Pressure
Positive-Pressure Respiration
Respiratory Insufficiency
Chronic Obstructive Pulmonary Disease
Ventilation
Disease Progression
Recurrence
Control Groups
Therapeutics

Keywords

  • COLD
  • Noninvasive mechanical ventilation
  • Respiratory failure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine

Cite this

Different modes of intermittent positive pressure ventilation (IPPV) in acute exacerbations of COLD patients. / Foglio, K.; Clini, E.; Vitacca, M.

In: Monaldi Archives for Chest Disease - Cardiac Series, Vol. 49, No. 6, 1994, p. 556-557.

Research output: Contribution to journalArticle

@article{d904a6ddebee43cbad96538137233bf4,
title = "Different modes of intermittent positive pressure ventilation (IPPV) in acute exacerbations of COLD patients",
abstract = "Patients with chronic obstructive lung disease may suffer from acute exacerbations of their disease, which may lead to acute respiratory failure necessitating endotracheal intubation and mechanical ventilation. We have compared retrospectively the results obtained with nasal positive pressure ventilation and those of standard medical therapy in acute relapses of severe COLD. The study showed that nasal IPPV (NIPPV) in control mode delivered for approximately 1 h, four times daily, six days a week over a 21 day period, does not result in independent improvement of acute exacerbation of COLD. In the next study the data seem to indicate, in apparent contrast, a marked reduction in the need for endotracheal intubation using noninvasive ventilation, both with assist-control and pressure support noninvasive modes, in comparison with an historical control group. We did not find a significant difference in the success rate of the two modes, but compliance to noninvasive ventilation was better with pressure support. In the former study patients showing neurological signs end requiring mechanical ventilation were excluded, while in the last study patients were selected on the basis of necessity of mechanical ventilation. The fact that in the last study, ventilation was applied by face mask instead of nasal mask may have influenced results. Further efforts are required to determine whether non-invasive ventilation is more a preventive measure to avoid endotracheal intubation, or is another means of delivering ventilatory support.",
keywords = "COLD, Noninvasive mechanical ventilation, Respiratory failure",
author = "K. Foglio and E. Clini and M. Vitacca",
year = "1994",
language = "English",
volume = "49",
pages = "556--557",
journal = "Monaldi Archives for Chest Disease",
issn = "1122-0643",
publisher = "Fondazione Salvatore Maugeri",
number = "6",

}

TY - JOUR

T1 - Different modes of intermittent positive pressure ventilation (IPPV) in acute exacerbations of COLD patients

AU - Foglio, K.

AU - Clini, E.

AU - Vitacca, M.

PY - 1994

Y1 - 1994

N2 - Patients with chronic obstructive lung disease may suffer from acute exacerbations of their disease, which may lead to acute respiratory failure necessitating endotracheal intubation and mechanical ventilation. We have compared retrospectively the results obtained with nasal positive pressure ventilation and those of standard medical therapy in acute relapses of severe COLD. The study showed that nasal IPPV (NIPPV) in control mode delivered for approximately 1 h, four times daily, six days a week over a 21 day period, does not result in independent improvement of acute exacerbation of COLD. In the next study the data seem to indicate, in apparent contrast, a marked reduction in the need for endotracheal intubation using noninvasive ventilation, both with assist-control and pressure support noninvasive modes, in comparison with an historical control group. We did not find a significant difference in the success rate of the two modes, but compliance to noninvasive ventilation was better with pressure support. In the former study patients showing neurological signs end requiring mechanical ventilation were excluded, while in the last study patients were selected on the basis of necessity of mechanical ventilation. The fact that in the last study, ventilation was applied by face mask instead of nasal mask may have influenced results. Further efforts are required to determine whether non-invasive ventilation is more a preventive measure to avoid endotracheal intubation, or is another means of delivering ventilatory support.

AB - Patients with chronic obstructive lung disease may suffer from acute exacerbations of their disease, which may lead to acute respiratory failure necessitating endotracheal intubation and mechanical ventilation. We have compared retrospectively the results obtained with nasal positive pressure ventilation and those of standard medical therapy in acute relapses of severe COLD. The study showed that nasal IPPV (NIPPV) in control mode delivered for approximately 1 h, four times daily, six days a week over a 21 day period, does not result in independent improvement of acute exacerbation of COLD. In the next study the data seem to indicate, in apparent contrast, a marked reduction in the need for endotracheal intubation using noninvasive ventilation, both with assist-control and pressure support noninvasive modes, in comparison with an historical control group. We did not find a significant difference in the success rate of the two modes, but compliance to noninvasive ventilation was better with pressure support. In the former study patients showing neurological signs end requiring mechanical ventilation were excluded, while in the last study patients were selected on the basis of necessity of mechanical ventilation. The fact that in the last study, ventilation was applied by face mask instead of nasal mask may have influenced results. Further efforts are required to determine whether non-invasive ventilation is more a preventive measure to avoid endotracheal intubation, or is another means of delivering ventilatory support.

KW - COLD

KW - Noninvasive mechanical ventilation

KW - Respiratory failure

UR - http://www.scopus.com/inward/record.url?scp=0028724962&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028724962&partnerID=8YFLogxK

M3 - Article

C2 - 7711716

AN - SCOPUS:0028724962

VL - 49

SP - 556

EP - 557

JO - Monaldi Archives for Chest Disease

JF - Monaldi Archives for Chest Disease

SN - 1122-0643

IS - 6

ER -