Abstract
Quantitative and qualitative evaluations of the distribution of mossy fiber terminals in the hippocampal regio inferior were performed in two inbred strains of mice, SECRe/J and C57BL/6, known to have different learning abilities. The results confirmed previous observations showing that there are fewer mossy fiber terminals along basal dendrites of the CA3 pyramidal cells in the high performer strain (SECRe/J). One additional, qualitative difference between the strains was found near the hilus and in particular at dorsal levels. Thus strands of mossy fiber terminals connecting the infra- and suprapyramidal mossy fiber layers were more significant and more randomly oriented in the C57BL/6 strain than in SECRe/J. In an otherwise laminar structure like the hippocampus this might have a similar functional importance as the quantitative differences.
| Original language | English |
|---|---|
| Pages (from-to) | 111-116 |
| Number of pages | 6 |
| Journal | Neuroscience Letters |
| Volume | 36 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 11 1983 |
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Keywords
- hippocampus
- inbred mice
- learning
- memory
- mossy fibers
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Different mossy fiber patterns in two inbred strains of mice : A functional hypothesis. / Gozzo, Stefano; Ammassari-Teule, Martine.
In: Neuroscience Letters, Vol. 36, No. 2, 11.04.1983, p. 111-116.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Different mossy fiber patterns in two inbred strains of mice
T2 - A functional hypothesis
AU - Gozzo, Stefano
AU - Ammassari-Teule, Martine
PY - 1983/4/11
Y1 - 1983/4/11
N2 - Quantitative and qualitative evaluations of the distribution of mossy fiber terminals in the hippocampal regio inferior were performed in two inbred strains of mice, SECRe/J and C57BL/6, known to have different learning abilities. The results confirmed previous observations showing that there are fewer mossy fiber terminals along basal dendrites of the CA3 pyramidal cells in the high performer strain (SECRe/J). One additional, qualitative difference between the strains was found near the hilus and in particular at dorsal levels. Thus strands of mossy fiber terminals connecting the infra- and suprapyramidal mossy fiber layers were more significant and more randomly oriented in the C57BL/6 strain than in SECRe/J. In an otherwise laminar structure like the hippocampus this might have a similar functional importance as the quantitative differences.
AB - Quantitative and qualitative evaluations of the distribution of mossy fiber terminals in the hippocampal regio inferior were performed in two inbred strains of mice, SECRe/J and C57BL/6, known to have different learning abilities. The results confirmed previous observations showing that there are fewer mossy fiber terminals along basal dendrites of the CA3 pyramidal cells in the high performer strain (SECRe/J). One additional, qualitative difference between the strains was found near the hilus and in particular at dorsal levels. Thus strands of mossy fiber terminals connecting the infra- and suprapyramidal mossy fiber layers were more significant and more randomly oriented in the C57BL/6 strain than in SECRe/J. In an otherwise laminar structure like the hippocampus this might have a similar functional importance as the quantitative differences.
KW - hippocampus
KW - inbred mice
KW - learning
KW - memory
KW - mossy fibers
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UR - http://www.scopus.com/inward/citedby.url?scp=0020522419&partnerID=8YFLogxK
U2 - 10.1016/0304-3940(83)90251-3
DO - 10.1016/0304-3940(83)90251-3
M3 - Article
C2 - 6306516
AN - SCOPUS:0020522419
VL - 36
SP - 111
EP - 116
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 2
ER -