Different sleep onset criteria at the multiple sleep latency test (MSLT): An additional marker to differentiate central nervous system (CNS) hypersomnias

Fabio Pizza, Stefano Vandi, Stefania Detto, Francesca Poli, Christian Franceschini, Pasquale Montagna, Giuseppe Plazzi

Research output: Contribution to journal › Article

Abstract

Excessive daytime sleepiness (EDS) has different correlates in non-rapid eye movement (NREM) [idiopathic hypersomnia (IH) without long sleep time] and REM sleep [narcolepsy without cataplexy (NwoC) and narcolepsy with cataplexy (NC)]-related hypersomnias of central origin. We analysed sleep onset characteristics at the multiple sleep latency test (MSLT) applying simultaneously two sleep onset criteria in 44 NC, seven NwoC and 16 IH consecutive patients referred for subjective EDS complaint. Sleep latency (SL) at MSLT was assessed both as the time elapsed to the occurrence of a single epoch of sleep Stage 1 NREM (SL) and of unequivocal sleep [three sleep Stage 1 NREM epochs or any other sleep stage epoch, sustained SL (SusSL)]. Idiopathic hypersomnia patients showed significantly (P

Original languageEnglish
Pages (from-to)250-256
Number of pages7
JournalJournal of Sleep Research
Volume20
Issue number1 PART II
DOIs
Publication statusPublished - Mar 2011

Keywords

  • Idiopathic hypersomnia without long sleep time
  • Multiple sleep latency test (MSLT)
  • Narcolepsy with cataplexy
  • Narcolepsy without cataplexy
  • Sleep onset
  • Sleepiness

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Cognitive Neuroscience
  • Medicine(all)

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