TY - JOUR
T1 - Different spatial memory systems are involved in small-and large-scale environments
T2 - Evidence from patients with temporal lobe epilepsy
AU - Piccardi, L.
AU - Berthoz, A.
AU - Baulac, M.
AU - Denos, M.
AU - Dupont, S.
AU - Samson, S.
AU - Guariglia, C.
PY - 2010/10
Y1 - 2010/10
N2 - Recent reports show that humans and animals do not acquire information about routes and object locations in the same way. In spatial memory, a specific sub-system is hypothesized to be involved in encoding, storing and recalling navigational information, and it is segregated from the sub-system devoted to small-scale environment. We assessed this hypothesis in a sample of patients treated surgically for intractable temporal lobe epilepsy. We found double dissociations between learning and recall of spatial positions in large space versus small space. These results strongly support the hypothesis that two segregate systems process navigational memory for large-scale environments and spatial memory in small-scale environments.
AB - Recent reports show that humans and animals do not acquire information about routes and object locations in the same way. In spatial memory, a specific sub-system is hypothesized to be involved in encoding, storing and recalling navigational information, and it is segregated from the sub-system devoted to small-scale environment. We assessed this hypothesis in a sample of patients treated surgically for intractable temporal lobe epilepsy. We found double dissociations between learning and recall of spatial positions in large space versus small space. These results strongly support the hypothesis that two segregate systems process navigational memory for large-scale environments and spatial memory in small-scale environments.
KW - Corsi Block-Tapping Test
KW - Hippocampal patients
KW - Human navigation
KW - Object-location memory
KW - Topographical memory
UR - http://www.scopus.com/inward/record.url?scp=77957658518&partnerID=8YFLogxK
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U2 - 10.1007/s00221-010-2234-2
DO - 10.1007/s00221-010-2234-2
M3 - Article
C2 - 20445967
AN - SCOPUS:77957658518
VL - 206
SP - 171
EP - 177
JO - Experimental Brain Research
JF - Experimental Brain Research
SN - 0014-4819
IS - 2
ER -