Abstract
Background - Reappearance of low-frequency (LF) (±0.10 Hz) oscillations in RR interval (RR) after cardiac transplantation is indicative of sympathetic efferent reinnervation. We hypothesized that restored LF oscillations in RR in heart transplant recipients (HTRs) are linked to oscillations in muscle sympathetic nerve traffic (MSNA). Methods and Results - RR, RR variability, and MSNA were recorded 5±2 months (n=7, short-term HTRs) and 138±8 months (n=7, long-term HTRs) after heart transplantation and compared with matched hypertensive patients (n=7). A coherence function determined the coupling between LF oscillations in MSNA and RR. RR variance did not differ between short-term and long-term HTRs. However, LF variability was only 1±0.5 ms2 in the short-term HTRs but was 15±8 ms2 in the long-term HTRs (P
| Original language | English |
|---|---|
| Pages (from-to) | 1809-1813 |
| Number of pages | 5 |
| Journal | Circulation |
| Volume | 104 |
| Issue number | 15 |
| Publication status | Published - Oct 9 2001 |
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Keywords
- Circulation
- Nervous system, sympathetic
- Transplantation
ASJC Scopus subject areas
- Physiology
- Cardiology and Cardiovascular Medicine
Cite this
Differential characteristics of neural circulatory control : Early versus late after cardiac transplantation. / Van De Borne, Philippe; Neubauer, Jolanta; Rahnama, Mohsen; Jansens, Jean Luc; Montano, Nicola; Porta, Alberto; Somers, Virend K.; Degaute, Jean Paul.
In: Circulation, Vol. 104, No. 15, 09.10.2001, p. 1809-1813.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Differential characteristics of neural circulatory control
T2 - Early versus late after cardiac transplantation
AU - Van De Borne, Philippe
AU - Neubauer, Jolanta
AU - Rahnama, Mohsen
AU - Jansens, Jean Luc
AU - Montano, Nicola
AU - Porta, Alberto
AU - Somers, Virend K.
AU - Degaute, Jean Paul
PY - 2001/10/9
Y1 - 2001/10/9
N2 - Background - Reappearance of low-frequency (LF) (±0.10 Hz) oscillations in RR interval (RR) after cardiac transplantation is indicative of sympathetic efferent reinnervation. We hypothesized that restored LF oscillations in RR in heart transplant recipients (HTRs) are linked to oscillations in muscle sympathetic nerve traffic (MSNA). Methods and Results - RR, RR variability, and MSNA were recorded 5±2 months (n=7, short-term HTRs) and 138±8 months (n=7, long-term HTRs) after heart transplantation and compared with matched hypertensive patients (n=7). A coherence function determined the coupling between LF oscillations in MSNA and RR. RR variance did not differ between short-term and long-term HTRs. However, LF variability was only 1±0.5 ms2 in the short-term HTRs but was 15±8 ms2 in the long-term HTRs (P
AB - Background - Reappearance of low-frequency (LF) (±0.10 Hz) oscillations in RR interval (RR) after cardiac transplantation is indicative of sympathetic efferent reinnervation. We hypothesized that restored LF oscillations in RR in heart transplant recipients (HTRs) are linked to oscillations in muscle sympathetic nerve traffic (MSNA). Methods and Results - RR, RR variability, and MSNA were recorded 5±2 months (n=7, short-term HTRs) and 138±8 months (n=7, long-term HTRs) after heart transplantation and compared with matched hypertensive patients (n=7). A coherence function determined the coupling between LF oscillations in MSNA and RR. RR variance did not differ between short-term and long-term HTRs. However, LF variability was only 1±0.5 ms2 in the short-term HTRs but was 15±8 ms2 in the long-term HTRs (P
KW - Circulation
KW - Nervous system, sympathetic
KW - Transplantation
UR - http://www.scopus.com/inward/record.url?scp=0035834085&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035834085&partnerID=8YFLogxK
M3 - Article
C2 - 11591619
AN - SCOPUS:0035834085
VL - 104
SP - 1809
EP - 1813
JO - Circulation
JF - Circulation
SN - 0009-7322
IS - 15
ER -