Differential characteristics of neural circulatory control: Early versus late after cardiac transplantation

Philippe Van De Borne, Jolanta Neubauer, Mohsen Rahnama, Jean Luc Jansens, Nicola Montano, Alberto Porta, Virend K. Somers, Jean Paul Degaute

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Background - Reappearance of low-frequency (LF) (±0.10 Hz) oscillations in RR interval (RR) after cardiac transplantation is indicative of sympathetic efferent reinnervation. We hypothesized that restored LF oscillations in RR in heart transplant recipients (HTRs) are linked to oscillations in muscle sympathetic nerve traffic (MSNA). Methods and Results - RR, RR variability, and MSNA were recorded 5±2 months (n=7, short-term HTRs) and 138±8 months (n=7, long-term HTRs) after heart transplantation and compared with matched hypertensive patients (n=7). A coherence function determined the coupling between LF oscillations in MSNA and RR. RR variance did not differ between short-term and long-term HTRs. However, LF variability was only 1±0.5 ms2 in the short-term HTRs but was 15±8 ms2 in the long-term HTRs (P

Original languageEnglish
Pages (from-to)1809-1813
Number of pages5
JournalCirculation
Volume104
Issue number15
Publication statusPublished - Oct 9 2001

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Heart Transplantation
Muscles
Transplant Recipients

Keywords

  • Circulation
  • Nervous system, sympathetic
  • Transplantation

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Van De Borne, P., Neubauer, J., Rahnama, M., Jansens, J. L., Montano, N., Porta, A., ... Degaute, J. P. (2001). Differential characteristics of neural circulatory control: Early versus late after cardiac transplantation. Circulation, 104(15), 1809-1813.

Differential characteristics of neural circulatory control : Early versus late after cardiac transplantation. / Van De Borne, Philippe; Neubauer, Jolanta; Rahnama, Mohsen; Jansens, Jean Luc; Montano, Nicola; Porta, Alberto; Somers, Virend K.; Degaute, Jean Paul.

In: Circulation, Vol. 104, No. 15, 09.10.2001, p. 1809-1813.

Research output: Contribution to journalArticle

Van De Borne, P, Neubauer, J, Rahnama, M, Jansens, JL, Montano, N, Porta, A, Somers, VK & Degaute, JP 2001, 'Differential characteristics of neural circulatory control: Early versus late after cardiac transplantation', Circulation, vol. 104, no. 15, pp. 1809-1813.
Van De Borne, Philippe ; Neubauer, Jolanta ; Rahnama, Mohsen ; Jansens, Jean Luc ; Montano, Nicola ; Porta, Alberto ; Somers, Virend K. ; Degaute, Jean Paul. / Differential characteristics of neural circulatory control : Early versus late after cardiac transplantation. In: Circulation. 2001 ; Vol. 104, No. 15. pp. 1809-1813.
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T2 - Early versus late after cardiac transplantation

AU - Van De Borne, Philippe

AU - Neubauer, Jolanta

AU - Rahnama, Mohsen

AU - Jansens, Jean Luc

AU - Montano, Nicola

AU - Porta, Alberto

AU - Somers, Virend K.

AU - Degaute, Jean Paul

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N2 - Background - Reappearance of low-frequency (LF) (±0.10 Hz) oscillations in RR interval (RR) after cardiac transplantation is indicative of sympathetic efferent reinnervation. We hypothesized that restored LF oscillations in RR in heart transplant recipients (HTRs) are linked to oscillations in muscle sympathetic nerve traffic (MSNA). Methods and Results - RR, RR variability, and MSNA were recorded 5±2 months (n=7, short-term HTRs) and 138±8 months (n=7, long-term HTRs) after heart transplantation and compared with matched hypertensive patients (n=7). A coherence function determined the coupling between LF oscillations in MSNA and RR. RR variance did not differ between short-term and long-term HTRs. However, LF variability was only 1±0.5 ms2 in the short-term HTRs but was 15±8 ms2 in the long-term HTRs (P

AB - Background - Reappearance of low-frequency (LF) (±0.10 Hz) oscillations in RR interval (RR) after cardiac transplantation is indicative of sympathetic efferent reinnervation. We hypothesized that restored LF oscillations in RR in heart transplant recipients (HTRs) are linked to oscillations in muscle sympathetic nerve traffic (MSNA). Methods and Results - RR, RR variability, and MSNA were recorded 5±2 months (n=7, short-term HTRs) and 138±8 months (n=7, long-term HTRs) after heart transplantation and compared with matched hypertensive patients (n=7). A coherence function determined the coupling between LF oscillations in MSNA and RR. RR variance did not differ between short-term and long-term HTRs. However, LF variability was only 1±0.5 ms2 in the short-term HTRs but was 15±8 ms2 in the long-term HTRs (P

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