Abstract
Performances of totally implantable infusion systems were analyzed in patients with colorectal liver metastases undergoing intra-arterial treatment. It consisted of 14-day continuous infusion of 5-fluor-2'deoxyuridine with pumps (pump14, 44 patients) or ports fed by external pumps (port14, 34 patients), or bolus infusion of cisplatin (port21, 57 patients) or epirubicin (port7, 22 patients) every 3rd week and weekly, respectively. Toxicity and disease progression were the most common causes of treatment interruption. System failure occurred in 2 pump14, 9 port14, 6 port21 and 2 port7 cases. Pocket problems were most frequent in the pump14 group (30%), whereas catheter- and infusion-related problems were mostly observed in the port14 group (109%). The devices were still functional after 12 months in 92% of pump14, 24% of port14, 65% of port21 and in 78% of port7 patients. Although implantable ports allow adequate infusion periods, in most cases they appear especially suitable for bolus infusions.
| Original language | English |
|---|---|
| Pages (from-to) | 26-33 |
| Number of pages | 8 |
| Journal | European Surgical Research |
| Volume | 30 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1998 |
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Keywords
- Colorectal neoplasms
- Implantable devices
- Infusion pumps
- Infusions, intra-arterial
- Liver neoplasms
ASJC Scopus subject areas
- Surgery
Cite this
Differential device performances for hepatic arterial chemotherapy : A technical report on totally implantable pumps and ports for both continuous and bolus infusion. / Civalleri, D.; DeCian, F.; Pellicci, R.; Balletto, Nadia; Simoni, G.; Cosimelli, M.; Mondini, G.; Bignami, Paola; Cagol, P. P.
In: European Surgical Research, Vol. 30, No. 1, 01.1998, p. 26-33.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Differential device performances for hepatic arterial chemotherapy
T2 - A technical report on totally implantable pumps and ports for both continuous and bolus infusion
AU - Civalleri, D.
AU - DeCian, F.
AU - Pellicci, R.
AU - Balletto, Nadia
AU - Simoni, G.
AU - Cosimelli, M.
AU - Mondini, G.
AU - Bignami, Paola
AU - Cagol, P. P.
PY - 1998/1
Y1 - 1998/1
N2 - Performances of totally implantable infusion systems were analyzed in patients with colorectal liver metastases undergoing intra-arterial treatment. It consisted of 14-day continuous infusion of 5-fluor-2'deoxyuridine with pumps (pump14, 44 patients) or ports fed by external pumps (port14, 34 patients), or bolus infusion of cisplatin (port21, 57 patients) or epirubicin (port7, 22 patients) every 3rd week and weekly, respectively. Toxicity and disease progression were the most common causes of treatment interruption. System failure occurred in 2 pump14, 9 port14, 6 port21 and 2 port7 cases. Pocket problems were most frequent in the pump14 group (30%), whereas catheter- and infusion-related problems were mostly observed in the port14 group (109%). The devices were still functional after 12 months in 92% of pump14, 24% of port14, 65% of port21 and in 78% of port7 patients. Although implantable ports allow adequate infusion periods, in most cases they appear especially suitable for bolus infusions.
AB - Performances of totally implantable infusion systems were analyzed in patients with colorectal liver metastases undergoing intra-arterial treatment. It consisted of 14-day continuous infusion of 5-fluor-2'deoxyuridine with pumps (pump14, 44 patients) or ports fed by external pumps (port14, 34 patients), or bolus infusion of cisplatin (port21, 57 patients) or epirubicin (port7, 22 patients) every 3rd week and weekly, respectively. Toxicity and disease progression were the most common causes of treatment interruption. System failure occurred in 2 pump14, 9 port14, 6 port21 and 2 port7 cases. Pocket problems were most frequent in the pump14 group (30%), whereas catheter- and infusion-related problems were mostly observed in the port14 group (109%). The devices were still functional after 12 months in 92% of pump14, 24% of port14, 65% of port21 and in 78% of port7 patients. Although implantable ports allow adequate infusion periods, in most cases they appear especially suitable for bolus infusions.
KW - Colorectal neoplasms
KW - Implantable devices
KW - Infusion pumps
KW - Infusions, intra-arterial
KW - Liver neoplasms
UR - http://www.scopus.com/inward/record.url?scp=0031975727&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031975727&partnerID=8YFLogxK
U2 - 10.1159/000008554
DO - 10.1159/000008554
M3 - Article
C2 - 9493691
AN - SCOPUS:0031975727
VL - 30
SP - 26
EP - 33
JO - European Surgical Research
JF - European Surgical Research
SN - 0014-312X
IS - 1
ER -