Differential diagnosis of lung nodules: Breast cancer metastases and lung tuberculosis

Mauro Endri, Giuseppe Cartei, Fable Zustovich, Francesco Saverio Serino, Ambrogio Fassina

Research output: Contribution to journalArticlepeer-review


In a follow-up a 74-year-old woman with breast cancer (clinical stage T4N1M0 at onset, treatment by surgical resection and tamoxifen) presented a combination of two distinct diseases in the lung: breast cancer metastasis and tuberculosis. A CT scan showed multiple pulmonary nodular lesions and in only one lesion fine needle aspiration cytology (FNAC) diagnosed tuberculosis. After specific antibiotic therapy, isoniazide and rifampin, a CT scan highlighted disappearance of tubercular lesion. Because occurrence of tuberculosis during chemo or hormone therapy for metastatic breast cancer is rare, the present case is note-worthy. Indeed, it is worth pointing out the differential diagnosis of pulmonary nodular lesions in patients with cancer and the possible reactivation of tuberculosis even in patients without specific symptoms, without typical tubercular radiological features.

Original languageEnglish
Pages (from-to)39-42
Number of pages4
JournalInfezioni in Medicina
Issue number1
Publication statusPublished - Mar 2010


  • Breast cancer
  • Metastases
  • Pulmonary nodular lesions
  • Tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases


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