Differential diagnosis of multiple sclerosis: Contribution of magnetic resonance techniques

F. Triulzi, G. Scotti

Research output: Contribution to journalArticlepeer-review


It is widely accepted that magnetic resonance imaging (MRI) findings are not totally specific for the diagnosis of multiple sclerosis. White matter lesions that mimic those of multiple sclerosis may be detected in both normal volunteers and patients harbouring different diseases. Virtually all the characteristic features of multiple sclerosis are sometimes encountered in other conditions affecting predominantly the white matter. Different conditions such as vasculitis, subcortical atherosclerotic leukoencephalopathy, Lyme disease, or acute disseminated encephalomyelitis can be virtually indistinguishable from multiple sclerosis on conventional MR images. Also the FLAIR technique adds little to the differential diagnosis. The calculation of magnetisation transfer ratio (MT ratio) may be useful to better characterise some entities, such as vasculitis, from multiple sclerosis.

Original languageEnglish
JournalJournal of Neurology, Neurosurgery and Psychiatry
Issue numberSUPPL. 1
Publication statusPublished - May 1998


  • Brain
  • Demyelinating diseases
  • Magnetic resonance imaging
  • Multiple sclerosis
  • Vasculitis

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)
  • Psychiatry and Mental health


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