Diagnóstico diferencial de los prolactinomas

Translated title of the contribution: Differential diagnosis of prolactinomas

Marco Losa, Paolo Ribotto

Research output: Contribution to journalArticlepeer-review


Hyperprolactinemia may be due to both prolactin-secreting pituitary adenomas (prolactinomas) and nonfunctioning sellar tumors (so-called pseudoprolactinomas). The ratio between the size of the lesion and the degree of hyperprolactinemia usually allows prolactinomas to be distinguished from pseudoprolactinomas; this differential diagnosis is essential, since therapy is entirely different in each case (medical in the former, surgical in the latter). The possible coexistence of other physiologic, pathologic or iatrogenic causes for hyperprolactinemia, as well as laboratory artifacts (hook effect) and the presence of prolactin variants devoid of biological activity (macroprolactins) can give rise to errors. Clinicians should be aware of these conditions, since inappropriate treatments can result if they are not recognized. Copyrigth

Translated title of the contributionDifferential diagnosis of prolactinomas
Original languageSpanish
Pages (from-to)342-345
Number of pages4
Issue number4
Publication statusPublished - Jun 2011


  • Nonfunctioning pituitary adenomas
  • Pituitary neoplasm
  • Pituitary surgery
  • Prolactin

ASJC Scopus subject areas

  • Medicine(all)


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