Differential effects of gamma interferon on expression of HLA class II molecules controlled by the DR and DC loci

F. Ameglio, M. R. Capobianchi, A. Dolei, R. Tosti

Research output: Contribution to journalArticlepeer-review

Abstract

Interferon-γ affected the expression of the products of the immunoassociated antigen complex by a differential modulation of DR- and DC-locus-controlled molecules. In melanoma M14 cells treated with interferon-γ, levels of DR molecules were increased two- to threefold, whereas levels of DC molecules were increased six- to sevenfold. Similar effects were induced on the two allelic products of each locus.

Original languageEnglish
Pages (from-to)122-125
Number of pages4
JournalInfection and Immunity
Volume42
Issue number1
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Immunology

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