Interferon-γ affected the expression of the products of the immunoassociated antigen complex by a differential modulation of DR- and DC-locus-controlled molecules. In melanoma M14 cells treated with interferon-γ, levels of DR molecules were increased two- to threefold, whereas levels of DC molecules were increased six- to sevenfold. Similar effects were induced on the two allelic products of each locus.
|Number of pages||4|
|Journal||Infection and Immunity|
|Publication status||Published - 1983|
ASJC Scopus subject areas