Differential postnatal development of μ-, δ- and χ-opioid binding sites in mouse brain

Alessandra Tavani, Linda E. Robson, Hans W. Kosterlitz

Research output: Contribution to journalArticlepeer-review

Abstract

By selective labelling techniques together with analysis of saturation curves it is shown that the concentrations of the μ-, δ- and χ-binding sites increase during postnatal development particularly in the first few weeks after birth. There are little or no changes in affinity. The rate of development is different for each type of site. The most striking finding is that the development of μ- and χ-sites precedes that of δ-sites.

Original languageEnglish
Pages (from-to)306-309
Number of pages4
JournalDevelopmental Brain Research
Volume23
Issue number2
DOIs
Publication statusPublished - 1985

Keywords

  • binding affinity
  • maximum binding capacity
  • mouse brain homogenate
  • opioid binding site
  • postnatal development
  • μ-, δ- and χ-sites

ASJC Scopus subject areas

  • Developmental Biology
  • Developmental Neuroscience

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