Difficult clinical challenges in haemophilia: International experiential perspectives

Angela L. Forsyth, Paul Giangrande, Charles R M Hay, Gili Kenet, Craig M. Kessler, Paul N. Knöbl, Adolfo Llinás, Elena Santagostino, Guy Young

Research output: Contribution to journalArticlepeer-review


Haemostasis management in people with haemophilia can present a range of challenges to physicians. Specific challenges that may be encountered relate to regimens for immune tolerance induction, use of central venous access devices, optimizing care of paediatric patients with inhibitors and improving outcomes in acquired haemophilia. There are also challenges related to performing surgery, and the establishment of specialist centres is valuable with regard to this. These challenges are considered in the light of available data, and with perspectives gained from the experience of experts treating patients around the world. Sharing this knowledge may help to improve patient management.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
Issue numberSUPPL.5
Publication statusPublished - Jul 2012


  • Acquired haemophilia
  • Elective orthopaedic surgery
  • Haemophilia
  • Immune tolerance
  • Inhibitors
  • Paediatric

ASJC Scopus subject areas

  • Hematology
  • Genetics(clinical)


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